1. Three ways ex-CDC chief says that Trump team is sidelining science

2. Wired for growth: neuron–tumour signalling in the lung and brain increases growth of a hard-to-treat cancer

3. Will the public support basic science? A new non-profit aims to find out

4. Years of hits to the head prime the brain for decline

5. Earth’s atmosphere took two billion years to become fully oxygenated

6. Bioelectronic implants built from rolled-up stretchy circuits

7. Pharmaceutical giants pull out of UK: why it matters for global science

8. Bespoke 3D printing adapted to features mapped using computer vision

9. Secrets of DeepSeek AI model revealed in landmark paper

10. AI can learn to show its workings through trial and error

11. People are more likely to cheat when they delegate tasks to AI

12. Bring us your LLMs: why peer review is good for AI models

13. Which diseases will you have in 20 years? This AI makes accurate predictions

14. A photonic chip enables ultrabroadband wireless communication

15. A surprising way to make heat in an unexpected part of fat cells

16. Caribbean coral reefs are threatened by rising seas

17. A domed pachycephalosaur from the early Cretaceous of Mongolia

18. Peroxisomal metabolism of branched fatty acids regulates energy homeostasis

19. Co-option of an ancestral cloacal regulatory landscape during digit evolution

20. Learning the natural history of human disease with generative transformers

21. Delegation to artificial intelligence can increase dishonest behaviour

22. Structural basis for mTORC1 activation on the lysosomal membrane

23. DeepSeek-R1 incentivizes reasoning in LLMs through reinforcement learning

24. Reduced Atlantic reef growth past 2 C warming amplifies sea-level impacts

25. High-density soft bioelectronic fibres for multimodal sensing and stimulation

26. A room temperature rechargeable all-solid-state hydride ion battery

27. Myeloperoxidase transforms chromatin into neutrophil extracellular traps

28. Selective presynaptic inhibition of leg proprioception in behaving Drosophila

29. Covariation MS uncovers a protein that controls cysteine catabolism

30. Stratified wind from a super-Eddington X-ray binary is slower than expected

31. Atomic-scale imaging of frequency-dependent phonon anisotropy

32. A movable long-term implantable soft microfibre for dynamic bioelectronics

33. Transitions in dynamical regime and neural mode during perceptual decisions

34. Toughened self-assembled monolayers for durable perovskite solar cells

35. Addressing the safety of next-generation batteries

36. Engineered prime editors with minimal genomic errors

37. Repeated head trauma causes neuron loss and inflammation in young athletes

38. Analogue speech recognition based on physical computing

39. CRISPR activation for SCN2A-related neurodevelopmental disorders

40. A neuronal architecture underlying autonomic dysreflexia

41. Basal cell of origin resolves neuroendocrine–tuft lineage plasticity in cancer

42. This AI tool predicts your risk of 1,000 diseases — by looking at your medical records

43. A plant-forward menu is linked to lower diabetes risk

44. Can We Fix America’s Dementia Care Crisis before It’s Too Late?

45. Alzheimer’s Drugs Are Finally Tackling the Disease Itself. Here’s How

46. The Hidden Link between Racism and Alzheimer’s Risk

47. The Vexing Promise of New Blood Tests for Alzheimer’s

48. Can Diet and Exercise Really Prevent Alzheimer’s?

49. Controversial New Alzheimer’s Drugs Offer Hope—But at a High Cost

50. New Hope in Alzheimer’s Research

51. My career switch from psychologist to open-science advocate

52. The parable of the doors

53. Daily briefing: A ‘time crystal’ made visible to the naked eye

54. AI is helping to decode animals’ speech. Will it also let us talk with them?

55. Mysterious changes near Earth’s core revealed by satellites in space

56. Rare comet photobombs telescope’s view of the cosmos

57. Delta-type glutamate receptors are ligand-gated ion channels

58. Make trains great again — for the sake of people and the planet

59. Publisher Correction: TCF1 and LEF1 promote B-1a cell homeostasis and regulatory function

60. ‘Revolutionary’ AI tools rescue old weather data to improve climate models

61. Mysterious mass deaths of an extinct giant deer

62. Gone with the wind: deciphering how dandelions drive seed dispersal

63. Equity in science is a beautiful lie — and I’m done pretending

64. How billions of hacked mosquitoes and a vaccine could beat the deadly dengue virus

65. How did assaults on science become the norm — and what can we do?

66. Coordinate to combat Pakistan’s climate-driven disasters

67. A population plunge could help to mitigate the global biodiversity crisis

68. Impoundment of funds endangers US investment in science and medical research

69. Fertility declines are no cause for concern, history shows

70. Daily briefing: What’s next for gravitational-wave detectors?

71. Ssmoke-dried mummies pre-date Egypt’s embalmed bodies

72. Mirror of the unknown: should research on mirror-image molecular biology be stopped?

73. How should ‘mirror life’ research be restricted? Debate heats up

74. Continuous operation of a coherent 3,000-qubit system

75. The chatbots claiming to be Jesus: spreading gospel or heresy?

76. Sweet like chocolate: researching in the shade of a cacao tree

77. ‘Lipstick on a pig’: how to fight back against a peer-review bully

78. GPS timekeeping is increasingly vulnerable: here’s how to deliver future-proofed time

79. Weird ''time crystals'' are made visible at last

80. Publisher Correction: Experimental determination of partial charges with electron diffraction

81. Daily briefing: The most- and least-improved countries for chronic disease

82. Heroes or hoarders? The strange brains of people who collect

83. Ready or not, the digital afterlife is here

84. RFK Jr’s vaccine advisers will soon review four shots: what''s at stake

85. How to help refugees thrive: have local families host them

86. Songs of the striped mouse show who’s friend and who’s foe

87. Meet Europe''s first exascale supercomputer — can it compete in the global AI race?

88. LIGO is 10 years old: black-hole breakthroughs will ‘only get better’

89. Maintenance

90. Daily briefing: Heatwaves can be directly linked to emissions from specific companies

91. Why we launched Denmark’s second Young Academy (and what’s different about it)

92. Trump team disbands controversial US climate panel

93. AI tool detects LLM-generated text in research papers and peer reviews

94. Is my red your red? Neuroscience has an answer

95. Author Correction: A broad-spectrum lasso peptide antibiotic targeting the bacterial ribosome

96. Dinosaur egg dated directly for the first time

97. Daily briefing: Regenerative revolution aims to future-proof European agriculture

98. Tips and tricks to plan your career in science

99. Your risk of dying from chronic disease has dropped – if you live in these countries

100. These scientists left the US in Trump’s first term: their tips on taking the leap

101. Dozens of heatwaves linked to carbon emissions from specific companies

102. Jelly-filled garment keeps wearers cool when heat and humidity soar

103. Mystery Martian minerals hint at the planet’s complex geochemical past

104. Climate impacts are real — denying this is self-defeating

105. Clearest gravitational wave detection yet confirms Hawking’s black hole theory

106. A common gut fungus worsens infection with the food-borne bacterium Salmonella

107. Heatwaves linked to emissions of individual fossil-fuel and cement producers

108. ‘Brain dial’ turns food consumption on or off in mice

109. Epigenetic clues from cancer’s past foretell its future

110. Designing an alloy microstructure atom by atom to withstand extreme cold

111. How did the oldest star clusters form?

112. AI-generated medical data can sidestep usual ethics review, universities say

113. Synthetic data can benefit medical research — but risks must be recognized

114. Iron-respiring microbes could have a role in sulfur cycling

115. Probing the Kitaev honeycomb model on a neutral-atom quantum computer

116. Probing non-equilibrium topological order on a quantum processor

117. Structure and mechanism of the mitochondrial calcium transporter NCLX

118. Functional synapses between neurons and small cell lung cancer

119. Probing the heterogeneous nature of LiF in solid–electrolyte interphases

120. Myeloid progenitor dysregulation fuels immunosuppressive macrophages in tumours

121. Redox-driven mineral and organic associations in Jezero Crater, Mars

122. Systematic attribution of heatwaves to the emissions of carbon majors

123. Energy deficiency selects crowded live epithelial cells for extrusion

124. Observing differential spin currents by resonant inelastic X-ray scattering

125. Molecular subtypes of human skeletal muscle in cancer cachexia

126. Late fluid flow in a primitive asteroid revealed by Lu–Hf isotopes in Ryugu

127. Neuronal activity-dependent mechanisms of small cell lung cancer pathogenesis

128. ABCA7 variants impact phosphatidylcholine and mitochondria in neurons

129. Amplifying antigen-induced cellular responses with proximity labelling

130. Loss-of-function mutations in PLD4 lead to systemic lupus erythematosus

131. Fluctuating DNA methylation tracks cancer evolution at clinical scale

132. Stabilizing effect of amino acids on protein and colloidal dispersions

133. Programmable antisense oligomers for phage functional genomics

134. The emergence of globular clusters and globular-cluster-like dwarfs

135. Human gastroids to model regional patterning in early stomach development

136. The oldest known lepidosaur and origins of lepidosaur feeding adaptations

137. Long-range PM2.5 pollution and health impacts from the 2023 Canadian wildfires

138. Feeling the heat: fossil-fuel producers linked to dozens of heatwaves

139. Editorial Expression of Concern: Recovery of learning and memory is associated with chromatin remodelling

140. The earth will not consume our bones

141. Using biobanks to boost research: a how-to guide

142. Scientists take on Trump: the researchers fighting back

143. Daily briefing: Different people’s brains process colours in the same way

144. Protests are infectious: mapping rural unrest in Revolutionary France

145. Head start: fossil clues about how bodies evolved from two-fold to five-fold symmetry

146. Bug bites convince UK doctor to support mosquito research centre

147. AI chatbots are already biasing research — we must establish guidelines for their use now

148. A revolution is sweeping Europe’s farms: can it save agriculture?

149. Protecting science from sanctions

150. Strengthen the science behind the Agreement on Fisheries Subsidies

151. Life scientists: educate others to help strengthen biosecurity

152. Use computing royalties to kick-start biodiversity fund

153. Creativity is essential to the ethos of universities

154. Daily briefing: A polo-team’s worth of cloned CRISPR horses

155. These nations are wooing PhD students amid US funding uncertainties

156. How to make a ‘laser’ of neutrinos

157. My blue is your blue: different people’s brains process colours in the same way

158. Can researchers stop AI making up citations?

159. The surprising ways bridges resist collapse

160. Research misconduct: how the scientific community is fighting back

161. Iggy bop: how I tune in to the needs of Galápagos marine iguanas

162. ‘LinkedIn is like air to me’: the scientists who’ve cracked professional networking

163. ‘Amazing feat’: US man still alive six months after pig kidney transplant

164. Can a bold ‘social contract’ make data sharing more palatable?

165. How to build nature back better — read this manual

166. ‘Communities already have the solutions’: why I advocate for Indigenous knowledge

167. Rainer Weiss obituary: Nobel laureate who pioneered the technique that detected gravitational waves

168. Daily briefing: Nine metals in two dimensions

169. Daily briefing: Is a cure for psoriasis on the horizon?

170. Daily briefing: How bad are ultra-processed foods, really?

171. Nature goes inside the world’s largest ‘mosquito factory’ — here’s the buzz

172. First CRISPR horses spark controversy: what’s next for gene-edited animals?

173. Author Correction: PPP2R1A mutations portend improved survival after cancer immunotherapy

174. When AI rejects your grant proposal: algorithms are helping to make funding decisions

175. Hope for diabetes: CRISPR-edited cells pump out insulin in a person – and evade immune detection

176. Diabetes drug shows anti-ageing effects on chromsomes

177. Different flames

178. Publisher Correction: In situ light-field imaging of octopus locomotion reveals simplified control

179. RFK Jr. slings accusations and defends public-health upheaval at fiery hearing

180. Air pollution increases the risk of some types of dementia

181. Europe’s largest paper mill? 1,500 research articles linked to Ukrainian network

182. Changing tides ushered in the world’s first civilization

183. Chemists cram record nine metals into trendy 2D material

184. Newfound immune cell in mice hints at why inflammation spikes with old age

185. Will a child survive? Older siblings have a powerful influence

186. Brain tumours in mice grow more slowly when starved of key amino acid

187. How the brain’s amygdala reacts when making decisions to avoid losses

188. A way to determine how partial charges of atoms in a molecule are distributed

189. Marsquakes indicate that the inner core of the red planet is solid, not liquid

190. Flies evolved a shock-absorber tissue used during embryonic development

191. Ancient DNA clarifies the early history of the Slavs

192. Compression causes cancer cells to start spreading

193. Depriving brain tumours of an amino acid could enhance chemotherapy

194. Ant queens produce sons of two distinct species

195. The diversity of microbial enzymes that turn a pollutant into an inert gas

196. Earth’s capacity to store carbon could max out surprisingly soon

197. Damaged bridges flex and twist to prevent collapse

198. Cocaine-activated ion channels engineered to break the loop of addiction in rats

199. ‘Almost unimaginable’: these ants are different species but share a mother

200. Ancient DNA connects large-scale migration with the spread of Slavs

201. Seismic detection of a 600-km solid inner core in Mars

202. Rewiring of cortical glucose metabolism fuels human brain cancer growth

203. Dynamic fibroblast–immune interactions shape recovery after brain injury

204. One mother for two species via obligate cross-species cloning in ants

205. Genetic suppression features ABHD18 as a Barth syndrome therapeutic target

206. Multiple overlapping binding sites determine transcription factor occupancy

207. Amygdala–liver signalling orchestrates glycaemic responses to stress

208. Infrastructure deficits and informal settlements in sub-Saharan Africa

209. PICALM Alzheimer’s risk allele causes aberrant lipid droplets in microglia

210. Commensal yeast promotes Salmonella Typhimurium virulence

211. Supervised learning in DNA neural networks

212. 3D-printed micro ion trap technology for quantum information applications

213. Adaptive and context-aware volumetric printing

214. Training of physical neural networks

215. A nanobody specific to prefusion glycoprotein B neutralizes HSV-1 and HSV-2

216. Brain-wide representations of prior information in mouse decision-making

217. Patterned invagination prevents mechanical instability during gastrulation

218. Spatial joint profiling of DNA methylome and transcriptome in tissues

219. A circuit that integrates drive state and social contact to gate mating

220. Single-cell transcriptomic and genomic changes in the ageing human brain

221. Analog optical computer for AI inference and combinatorial optimization

222. Divergent evolutionary strategies pre-empt tissue collision in gastrulation

223. A brain-wide map of neural activity during complex behaviour

224. A prudent planetary limit for geologic carbon storage

225. DNA2 enables growth by restricting recombination-restarted replication

226. Latent resistance mechanisms of steel truss bridges after critical failures

227. Two ant species, one mother

228. Two ants, two species, one mother

229. Cas9 senses CRISPR RNA abundance to regulate CRISPR spacer acquisition

230. This is the world’s largest ‘mosquito factory’: its goal is to stop dengue

231. Inside a mosquito factory

232. Heart’s desire

233. Daily briefing: Epigenetic atlas shows how ageing tweaks DNA

234. How academics and ‘big tech’ can learn from one another

235. Are ultra-processed foods really so unhealthy? What the science says

236. Ultra-processed foods — it’s time for an improved definition

237. Liquid-crystal specs refocus with the push of a button

238. A mammoth toothache: world’s oldest bacterial DNA found in the mouths of mammoths

239. Daily briefing: Spouses tend to share the same psychiatric disorders

240. Experiment puts ‘spoon bending’ to the test

241. AI-powered brain device allows paralysed man to control robotic arm

242. Sexless seeds: how self-cloning crops could soon transform our food

243. These ‘glass straw’ optical fibres could speed up the Internet

244. Air taxis will soon be in our skies — if batteries can be made safer

245. Unifiying gravity and quantum theory requires better understanding of time

246. Veterinarians need to be part of West Nile disease storytelling

247. Include climate impacts when protecting infrastructure

248. China’s chikungunya virus outbreak is a wake up call

249. AI-agent ethics should consider sentient non-human animals

250. How ageing changes our genes — huge epigenetic atlas gives clearest picture yet

251. ‘The wolf is not the bad guy’: working with farmers to protect a reintroduced species

252. Who is afraid of quantum mechanics? Books in brief

253. Do social-media bans benefit young people? These data could offer clues

254. The grant lottery: award rates at UK national funding agency fall below 20%

255. Daily briefing: There are two kinds of beer drinkers — these are the flavours that divide them

256. Clarity or accuracy — what makes a good scientific image?

257. States now have a legal duty to prevent climate harm — justice is in reach

258. Trump called for ‘gold-standard science’: how the NIH, NSF and others are answering

259. When will life expectancy reach 100? No time soon

260. Spouses tend to share psychiatric disorders, massive study finds

261. The vibrant colours of a house-hunting crab — August’s best science image

262. Audio long read: How to detect consciousness in people, animals and maybe even AI

263. Hundreds of suspicious journals flagged by AI screening tool

264. Why scientists are flocking to Substack

265. How LinkedIn helped me to carve out a career path after my PhD

266. Author Correction: Dual neuromodulatory dynamics underlie birdsong learning

267. Daily briefing: Deliberate fearmongering spread like a virus through revolutionary France

268. Research posts on Bluesky are more original — and get better engagement

269. Even dinosaurs weren’t safe from this giant croc-like predator

270. Beer lovers fall into two flavour camps — which one are you in?

271. This deep-sea worm creates a toxic yellow pigment found in Rembrandt and Cézanne paintings

272. Author Correction: Endophilin marks and controls a clathrin-independent endocytic pathway

273. Daily briefing: What we know about autism and why it’s on the rise

274. How humans became upright: key changes to our pelvis found

275. Childhood eczema linked to mother’s stress during pregnancy

276. Deep gashes are tearing through cities, swallowing houses and displacing vast numbers of people

277. Glow-in-the-dark houseplants shine in rainbow of colours

278. Machine-learning model generates images using light

279. How tree shrews see the world

280. A spiky armoured dinosaur from Africa causes a rethink of ankylosaur evolution

281. How the pelvis evolved to enable human bipedalism

282. Gully formation in cities is displacing tens of thousands of people

283. Origins of life: the molecules that could have unlocked peptide synthesis

284. An abiding mystery of the French Revolution is solved — by epidemiology

285. A closer look at how cells sense dietary nutrients

286. Hazardous science that helps to save and improve lives needs more support

287. Epidemiology models explain rumour spreading during France’s Great Fear of 1789

288. Extreme armour in the world’s oldest ankylosaur

289. The evolution of hominin bipedalism in two steps

290. Optical generative models

291. Cocaine chemogenetics blunts drug-seeking by synthetic physiology

292. A compressed hierarchy for visual form processing in the tree shrew

293. Dual-scale chemical ordering for cryogenic properties in CoNiV-based alloys

294. Haematopoietic stem cell number is not solely defined by niche availability

295. Global phenology maps reveal the drivers and effects of seasonal asynchrony

296. Attosecond control and measurement of chiral photoionization dynamics

297. Microbial iron oxide respiration coupled to sulfide oxidation

298. Topological prethermal strong zero modes on superconducting processors

299. One-shot design of functional protein binders with BindCraft

300. Two-billion-year transitional oxygenation of the Earth’s surface