1. Publisher Correction: Physiology and immunology of a pig-to-human decedent kidney xenotransplant

2. Exercise rewires the brain — boosting the body’s endurance

3. The ‘astounding’ rise of semaglutide — and what’s next for weight-loss drugs

4. Flexible joints: robot morphs into a range of cyborg species

5. From ancient temples to bomb craters: explore Laos’s layered history — in photos

6. Self-powered vibration sensor for wearable health care and voice detection

7. Science funding needs fixing — but not through chaotic reforms

8. China to punish universities that fail to sanction research misconduct

9. Trump team’s new rule could make firing government scientists easier

10. My ‘detective’ job as a competitive-intelligence consultant for pharma

11. Author Correction: Inference and reconstruction of the heimdallarchaeial ancestry of eukaryotes

12. Four ways I ensured my research brought about real-world change

13. Clearing trapped cholesterol could relieve lymphoedema

14. Charge-neutral electrons are odd — except when they’re even

15. Squirrels could be a reservoir for the virus that causes mpox

16. Support people and their livelihoods rather than fossil-fuel industries

17. Immune cells could be protected from ‘exhaustion’ by flipping genetic switches

18. Ten years since the first reported observation of gravitational waves

19. Robust partitioning of cell contents by physical instabilities and biological clocks

20. Can the clean-energy revolution save us from climate catastrophe?

21. Hunter-gatherers took refuge in European ''water world'' for millennia

22. Babies at nursery shape each other’s microbiomes

23. Untapped catalytic ability of aluminium has been unlocked

24. Large-scale quantum communication networks with integrated photonics

25. Sub-part-per-trillion test of the Standard Model with atomic hydrogen

26. Sleep-dependent clearance of brain lipids by peripheral blood cells

27. Single-shot parity readout of a minimal Kitaev chain

28. Parity-doublet coherence times in optically trapped polyatomic molecules

29. Sub-second volumetric 3D printing by synthesis of holographic light fields

30. Striatum-wide dopamine encodes trajectory errors separated from value

31. Continuous-wave narrow-linewidth vacuum ultraviolet laser source

32. Lasting Lower Rhine–Meuse forager ancestry shaped Bell Beaker expansion

33. Giant magnetocaloric effect and spin supersolid in a metallic dipolar magnet

34. Targeting excessive cholesterol deposition alleviates secondary lymphoedema

35. SLAMF6 as a drug-targetable suppressor of T cell immunity against cancer

36. Months-long stability of the head-direction system

37. Astrocytes enable amygdala neural representations supporting memory

38. Fossil isotope evidence for trophic simplification on modern Caribbean reefs

39. Pre-incision structures reveal principles of DNA nucleotide excision repair

40. Conformational diversity and fully opening mechanism of native NMDA receptor

41. Maximizing perovskite electroluminescence with ordered 3D/2D heterojunction

42. Transmission of MPXV from fire-footed rope squirrels to sooty mangabeys

43. CSN5i-3 is an orthosteric molecular glue inhibitor of COP9 signalosome

44. Aluminium redox catalysis enables cyclotrimerization of alkynes

45. Tiny robot fish could swim through the body powered by ultrasound

46. An ancient Roman game board’s secrets are revealed — with AI’s help

47. These hungry immune cells tidy sleeping flies'' brains

48. Transferable enantioselectivity models from sparse data

49. African countries must take control of health policy

50. Daily briefing: Caffeine might reduce dementia risk and slow cognitive decline

51. 18,000,000 minutes

52. What drugs are safe during pregnancy? There’s a shocking lack of data

53. My professor said ‘Black people are not interested in the environment’. I set out to prove him wrong

54. What can I do if my idea has been plagiarized?

55. Tree rings and salt lakes give clues about ancient rainfall

56. How to rescue the aid industry: focus on conflict prevention, not just relief

57. Lab morale got you down? Try a handbook

58. Dozens of researchers will move to France from US following high-profile bid to lure talent

59. Public-speaking tips from the experts: what scientists can learn from comics, musicians and actors

60. China’s biotech boom: why the nation must collaborate to stay ahead

61. Marine protection in the Azores: a triumph for conservation and sustainability

62. Publishing less won’t save the research system

63. Preserving water under megacities is crucial — and urgent

64. Internet blackout: Iran’s academic shutdown

65. Coffee drinking linked to slower brain ageing

66. Daily briefing: The dark side of the battery boom

67. Daily briefing: Bonobo’s tea party is first demonstration of pretend play in a non-human

68. My mission to make life more user friendly for the disability community

69. Jupiter gets downsized — and squashed

70. How to stop the survey-taking AI chatbots that threaten to upend social science

71. The dark side of green technology: what do electric vehicles really cost?

72. Measles is raging worldwide: are you at risk?

73. Super-sniffer aeroplane finds oil fields’ hidden emissions

74. US grant applicants surge at prestigious European research agency

75. Epstein files reveal deeper ties to scientists than previously known

76. Cheap AI chatbots transform medical diagnoses in places with limited care

77. Author Correction: Environmentally driven immune imprinting protects against allergy

78. Briefing Chat: ''External lungs'' keep man alive for 48 hours until transplant

79. OpenClaw AI chatbots are running amok — these scientists are listening in

80. Daily briefing: Tumours use neurons as hotline to the brain

81. ‘We need to dismantle the stigma of alcohol dependence in academia’

82. Universities in exile: displaced scholars count the costs of starting afresh

83. Not just a chip off the old block: nanoparticles reveal odd traits

84. This bonobo had a pretend tea party — showing make believe isn’t just for humans

85. Beetle is locked in to an eternal dance ― with an ant

86. Publisher Correction: Colibactin-driven colon cancer requires adhesin-mediated epithelial binding

87. Is UK science in jeopardy? Huge funding reforms spark chaos and anxiety

88. Author Correction: PHGDH heterogeneity potentiates cancer cell dissemination and metastasis

89. NASA’s latest telescope is a feat of early-career leadership

90. First ‘practical PhDs’ awarded in China — for products rather than papers

91. These mysterious ridges could be the secret to younger skin

92. Daily briefing: More than one-third of cancer cases are preventable

93. Innovative CAR-T therapy destroys cancer cells without dangerous side effects

94. How a protein repurposes vitamin B12 as a light sensor

95. A way to gauge the equity of ocean-related initiatives

96. Immune cells from the gut drive development of Parkinson’s disease in the brain

97. Evolutionary insights into a skin fold

98. Atlantic ocean currents defied the ice age

99. How tumours trick the brain into shutting down cancer-fighting cells

100. Particle collisions cast light on how matter forms from seemingly empty space

101. Open-source AI tool beats giant LLMs in literature reviews — and gets citations right

102. Common genetic variants affect risk of a major cause of pregnancy loss

103. A tumour-to-brain pathway hinders anticancer defences

104. Machine learning slashes the testing needed to work out battery lifetimes

105. Chemical capture of diazo metabolites reveals biosynthetic hydrazone oxidation

106. Measuring spin correlation between quarks during QCD confinement

107. Efficient near-telomere-to-telomere assembly of nanopore simplex reads

108. Integrated structural dynamics uncover a new B12 photoreceptor activation mode

109. Mosquito–capsid interactions contribute to flavivirus vector specificity

110. Rete ridges form via evolutionarily distinct mechanisms in mammalian skin

111. Activated ATF6α is a hepatic tumour driver restricting immunosurveillance

112. Resolving intervalley gaps and many-body resonances in moiré superconductors

113. Cleavage of mRNAs by a minority of pachytene piRNAs improves sperm fitness

114. Regulation of STING activation by phosphoinositide and cholesterol

115. Imaging the sub-moiré potential using an atomic single electron transistor

116. Spin-wave band-pass filters for 6G communication

117. ZFTA–RELA ependymomas make itaconate to epigenetically drive fusion expression

118. Single-molecule dynamics of the TRiC chaperonin system in vivo

119. Contemporaneous mobile- and stagnant-lid tectonics on the Hadean Earth

120. Tumour–brain crosstalk restrains cancer immunity via a sensory–sympathetic axis

121. Phenome-wide analysis of copy number variants in 470,727 UK Biobank genomes

122. Parkinson’s disease as a somato-cognitive action network disorder

123. Imaging a terahertz superfluid plasmon in a two-dimensional superconductor

124. A pore-forming antiphage defence is activated by oligomeric phage proteins

125. Signatures of fractional charges via anyon–trions in twisted MoTe2

126. Bacterial immune activation via supramolecular assembly with phage triggers

127. Discovery Learning predicts battery cycle life from minimal experiments

128. Synthesizing scientific literature with retrieval-augmented language models

129. Large-scale analogue quantum simulation using atom dot arrays

130. Atmospheric H2 variability over the past 1,100 years

131. PtdIns(3,5)P2 is an endogenous ligand of STING in innate immune signalling

132. Biofluid biomarkers in Alzheimer’s disease and other neurodegenerative dementias

133. Regulatory grammar in human promoters uncovered by MPRA-based deep learning

134. Atlas-guided discovery of transcription factors for T cell programming

135. A universal concept for melting in mantle upwellings

136. These mysterious ridges could help skin regenerate

137. AI could transform research assessment — and some academics are worried

138. What my cave stay taught me about sensors

139. ‘It means I can sleep at night’: how sensors are helping to solve scientists’ problems

140. The smart sensors improving the world’s biggest cities

141. Eviction notice

142. Author Correction: Cotranslational assembly of protein complexes in eukaryotes revealed by ribosome profiling

143. NIH rolls back red tape on some experiments — spurring excitement and concern

144. Biodiversity conservation has an evidence problem — it’s time to fix it

145. Daily briefing: What people with no ‘mind’s eye’ can tell us about consciousness

146. Quantum computers will finally be useful: what’s behind the revolution

147. Author knows best? Top AI conference asks for self-ranked papers amid paper deluge

148. More than one-third of cancer cases are preventable, massive study finds

149. Ontogeny and transcriptional regulation of Thetis cells

150. Now is not the time to defund human fetal tissue research

151. A history of hocus pocus: witchcraft down the ages

152. Author Correction: Increasingly negative tropical water–interannual CO2 growth rate coupling

153. I know science can’t fix the world — here’s why I do it anyway

154. Many people have no mental imagery. What’s going on in their brains?

155. The ''bible for psychiatry'' is getting a rewrite: your guide to the next DSM

156. The global plastics treaty can be saved — here’s how to break the deadlock

157. Who does academic consulting serve?

158. Calling all scientists: Support your Iranian colleagues

159. Embrace diverse PhD supervision styles — but enforce essential standards

160. Daily briefing: Scientists delve into the smells of history

161. China’s relationship with foreign scientific powers is changing rapidly

162. OpenAI-backed firm to use ultrasound to read minds. Does the science stand up?

163. Long-lived remote ion-ion entanglement for scalable quantum repeaters

164. A broadly protective antibody targeting gammaherpesvirus gB

165. How learning handwriting trains the brain: the science behind the cursive wars

166. See the Sun expand and contract like a pufferfish — January’s best science images

167. Science finds its song

168. Daily briefing: Why we enjoy things more when they’re hard to get

169. Does AI already have human-level intelligence? The evidence is clear

170. Is this journal legitimate? This tool can help you decide

171. Are health influencers making us sick?

172. Author Correction: Albumin orchestrates a natural host defence mechanism against mucormycosis

173. This robot hand detaches and walks by itself

174. Briefing Chat: What Brazilian centenarians could reveal about the science of ageing

175. China is betting on ‘optical’ computer chips – will they power AI?

176. Largest galaxy survey yet confirms that the Universe is not clumpy enough

177. Daily briefing: Brain–immune crosstalk worsens the damage of heart attacks

178. How DeepMind''s genome AI could help solve rare disease mysteries

179. Can academia handle my religious faith?

180. Publisher Correction: Nanotyrannus and Tyrannosaurus coexisted at the close of the Cretaceous

181. Publisher Correction: A domed pachycephalosaur from the early Cretaceous of Mongolia

182. Light-powered bacteria become living chemical factories

183. Longevity is in the genes: half of lifespan is heritable

184. Still conscious? Brain marker signals when anaesthesia takes hold

185. Genetically engineered ‘stinkweed’ comes up roses for making seed oil

186. Author Correction: Hunter-gatherer sea voyages extended to remotest Mediterranean islands

187. 48 hours without lungs: artificial organ kept man alive until transplant

188. This AI has chemical expertise — and helps synthesize 35 new drugs and materials

189. ArXiv says submissions must be in English: are AI translators up for the job?

190. Five ways to make the academic workplace happier and healthier this year

191. Developmental convergence and divergence in human stem cell models of autism

192. Critical social media posts linked to retractions of scientific papers

193. AI chatbots are infiltrating social-science surveys — and getting better at avoiding detection

194. Damage from a heart attack comes from brain signals, mouse study suggests

195. A bendable AI chip for wearable technology

196. Pesticide cocktails negatively affect soil biodiversity

197. Expert-level test is a head-scratcher for AI

198. Alternative explanation for how celestial objects generate large-scale magnetic fields

199. Scraps of viral DNA in biobank samples reveal secrets of Epstein–Barr virus

200. A step towards building miniature human livers

201. Chill out: freezing temperatures produced by letting a stressed alloy relax

202. Structure and mechanism of the human bile acid transporter OSTα–OSTβ

203. Vagal blood volume receptors compensate for haemorrhage and posture change

204. Optical switching of a moiré Chern ferromagnet

205. Observation of a superfluid-to-insulator transition of bilayer excitons

206. Structures of Ostα/β reveal a unique fold and bile acid transport mechanism

207. Pre-assembly of biomolecular condensate seeds drives RSV replication

208. GlycoRNA complexed with heparan sulfate regulates VEGF-A signalling

209. A benchmark of expert-level academic questions to assess AI capabilities

210. Holistic motor control of zebra finch song syllable sequences

211. Disentangling multiple gas kinematic drivers in the Perseus galaxy cluster

212. Optical control over topological Chern number in moiré materials

213. A flexible digital compute-in-memory chip for edge intelligence

214. The Ocean Equity Index

215. Ferromagnet-like binary switching of a Stoner–Wohlfarth antiferromagnet

216. Optofluidic three-dimensional microfabrication and nanofabrication

217. Limit of atomic-resolution-tomography reconstruction of amorphous nanoparticles

218. Psychedelics elicit their effects by 5-HT2A receptor-mediated Gi signalling

219. Vacuum ultraviolet second-harmonic generation in NH4B4O6F crystal

220. A cross-population compendium of gene–environment interactions

221. A cavity-array microscope for parallel single-atom interfacing

222. Advancing regulatory variant effect prediction with AlphaGenome

223. Robust cytoplasmic partitioning by solving a cytoskeletal instability

224. A prophage-encoded abortive infection protein preserves host and prophage spread

225. Low-power integrated optical amplification through second-harmonic resonance

226. An X-ray-emitting protocluster at z 5.7 reveals rapid structure growth

227. A Cambrian soft-bodied biota after the first Phanerozoic mass extinction

228. PAF15–PCNA exhaustion governs the strand-specific control of DNA replication

229. Frequency reproducibility of solid-state thorium-229 nuclear clocks

230. Human and bacterial genetic variation shape oral microbiomes and health

231. Bandwidth-tuned Mott transition and superconductivity in moiré WSe2

232. Lasing of a cavity-based X-ray source

233. Pesticide residues alter taxonomic and functional biodiversity in soils

234. Population-scale sequencing resolves determinants of persistent EBV DNA

235. Environmentally driven immune imprinting protects against allergy

236. Optical control of integer and fractional Chern insulators

237. Cholinergic modulation of dopamine release drives effortful behaviour

238. Intestinal macrophages modulate synucleinopathy along the gut–brain axis

239. Accurate determination of the 3D atomic structure of amorphous materials

240. Radiation-tolerant atomic-layer-scale RF system for spaceborne communication

241. Multimodal learning with next-token prediction for large multimodal models

242. Prethermalization by random multipolar driving on a 78-qubit processor

243. Constraints on axion dark matter by distributed intercity quantum sensors

244. Projected impacts of climate change on malaria in Africa

245. How your brain chemistry rewards hard work

246. Technologies to give a clearer view of the lungs

247. How ‘forest bathing’ keeps lungs healthy

248. Could the regenerative power of the lungs help to reverse disease?

249. Six highlights from lung-health research

250. Treatments for idiopathic pulmonary fibrosis are on the horizon

251. Funding cuts could put research into emerging threats to lung health at risk

252. Exposome studies can improve lung health

253. Act now to clean up air

254. Preserving the respiratory system

255. The unfortunate embossing of Subsector XZ-74

256. Daily briefing: The battle over the identity of the first animals

257. Wikipedia is needed now more than ever, 25 years on

258. Deep-sea robots will search for source of mysterious ‘dark oxygen’

259. The surprisingly big health benefits of just a little exercise

260. How much exercise do you really need?

261. Still working at 107: supercentenarian study probes genetics of extreme longevity

262. Author Correction: Relatively warm deep-water formation persisted in the Last Glacial Maximum

263. Sensors are transforming the world — work together to maximize their benefits

264. Author Correction: Nutrient-sensing nuclear receptors coordinate autophagy

265. Daily briefing: Blister beetles hoodwink bees with floral smells

266. Volcanic personality: the man who recognized volcanoes as a planet-shaping force of nature

267. Would forced retirement solve the academic job crisis?

268. How to eat well and within Earth’s limits

269. What were the first animals? The fierce sponge–jelly battle that just won’t end

270. Spotting viral invaders in koala family trees

271. African science needs to cut reliance on foreign donors

272. Street-dog policy in India is barking up the wrong tree

273. Social-media bans: why corporate fines could backfire

274. Audio long read: ‘I rarely get outside’ — scientists ditch fieldwork in the age of AI

275. Scalable and multiplexed recorders of gene regulation dynamics across weeks

276. Why do women like me get diagnosed with ADHD late?

277. Quantum spinning effect observed in a levitating magnet

278. Defending endangered trees against climate change and hungry goats

279. Exceeding 1.5 C requires rethinking accountability in climate policy

280. As we breach 1.5 C, we must replace temperature limits with clean-energy targets

281. Daily briefing: Why cancer might protect against Alzheimer’s disease

282. Daily briefing: Largest ever ‘superposition’ pushes quantum boundary

283. Technology is changing how we write — and how we think about writing

284. Greenland is important for global research: what''s next for the island''s science?

285. Gladys Mae West obituary: mathematician who pioneered GPS technology

286. Briefing Chat: The canny cow that can use tools, and how babies share their microbiomes

287. What a 1-billion pledge means for CERN’s ambitious supercollider plans

288. Guinea-Bissau suspends a US-funded vaccine trial as African scientists question its motives

289. Marvellous microbes, memory and the multiverse: Books in brief

290. NIH ends support for some human fetal-tissue research – dismaying scientists

291. Exclusive: key NIH review panels due to lose all members by the end of 2026

292. Cancer might protect against Alzheimer’s — this protein helps explain why

293. Microplastic levels in the air have been overestimated, but are still a big concern

294. What your breath says about the bacteria in your gut

295. When two years of academic work vanished with a single click

296. ‘Bodies like ours aren’t considered in academia’

297. Canny cattle: at least one cow knows how to use tools

298. Daily briefing: Trump — one year in

299. Cause of vision loss discovered in overlooked genes

300. ‘Remote controlled’ proteins illuminate living cells