1. Brand-new colour created by tricking human eyes with laser

2. Exclusive: Trump team freezes new NSF awards — and could soon axe hundreds of grants

3. Signs of life on a distant planet? Not so fast, say these astronomers

4. Martian rock hints at ancient dense atmosphere

5. Microplastic pollution found in insect casing from 1971

6. Invasion of the ‘journal snatchers’: the firms that buy science publications and turn them rogue

7. Daily briefing: The first colossal squid caught on camera in its natural habitat

8. ‘Totally broken’: how Trump 2.0 has paralysed work at US science agencies

9. 25 million deaths: what could happen if the US ends global health funding

10. Whole-genome sequencing susses out rare diseases

11. Sowing solutions: my quest to save Kenya’s maize from a devastating invader

12. Author Correction: Continued Atlantic overturning circulation even under climate extremes

13. Why politicians manipulate statistics — and what to do about it

14. The lunatic is on the grass: Books in brief

15. Winner, winner, lab-made dinner! Team grows nugget-sized chicken chunk

16. ‘Big leap’ for Parkinson’s treatment: symptoms improve in stem-cells trials

17. SWOT satellite provides a finer view of climate-driving ocean dynamics

18. Highly sensitive method captures rare RNAs in blood to search for disease

19. Unlocking the diversity of wild and domesticated rice

20. Japan’s big bet on stem-cell therapies might soon pay off with breakthrough therapies

21. Clinical trials test the safety of stem-cell therapy for Parkinson’s disease

22. Don’t rush promising stem-cell therapies

23. Age-related blood condition counteracted with a common diabetes drug

24. The first observation of ‘plastic ice’ reveals unusual behaviour of water molecules

25. Negative thermal expansion and oxygen-redox electrochemistry

26. Phase I trial of hES cell-derived dopaminergic neurons for Parkinson’s disease

27. Low overlap of transcription factor DNA binding and regulatory targets

28. Wide-swath satellite altimetry unveils global submesoscale ocean dynamics

29. Deep Visual Proteomics maps proteotoxicity in a genetic liver disease

30. Generation of human adult hepatocyte organoids with metabolic functions

31. Towards multimodal foundation models in molecular cell biology

32. Re-adenylation by TENT5A enhances efficacy of SARS-CoV-2 mRNA vaccines

33. Histone H1 deamidation facilitates chromatin relaxation for DNA repair

34. Perturbing LSD1 and WNT rewires transcription to synergistically induce AML differentiation

35. Antiferromagnetic quantum anomalous Hall effect under spin flips and flops

36. The growing memristor industry

37. Chromosome end protection by RAP1-mediated inhibition of DNA-PK

38. Phase I/II trial of iPS-cell-derived dopaminergic cells for Parkinson’s disease

39. Driven bright solitons on a mid-infrared laser chip

40. A sharp volatile-rich cap to the Yellowstone magmatic system

41. Subnanosecond flash memory enabled by 2D-enhanced hot-carrier injection

42. Observation of the axion quasiparticle in 2D MnBi2Te4

43. An ultrasensitive method for detection of cell-free RNA

44. Structure of the ATP-driven methyl-coenzyme M reductase activation complex

45. A pangenome reference of wild and cultivated rice

46. Multi-zonal liver organoids from human pluripotent stem cells

47. Electric-field-induced domain walls in wurtzite ferroelectrics

48. Metformin reduces the competitive advantage of Dnmt3aR878H HSPCs

49. The phased pan-genome of tetraploid European potato

50. Bovine H5N1 binds poorly to human-type sialic acid receptors

51. Natively expressed AcrIII-1 does not function as an anti-CRISPR protein

52. Receptor-binding specificity of a bovine influenza A virus

53. What a trove of potato genomes reveals about the humble spud

54. A. J. Eisfeld et al. reply

55. Mitochondrial metabolism sustains DNMT3A-R882-mutant clonal haematopoiesis

56. Reply to: Natively expressed AcrIII-1 does not function as an anti-CRISPR protein

57. Spain adapts to new reality as climate crisis hits home

58. Meet the researchers pioneering Spanish climate solutions

59. Healthy soil is the hidden ingredient — here’s how I’m fighting to save it

60. How a hydrogen lab is helping to power Spain’s green-energy shift

61. The future of Alzheimer’s treatment

62. Do infections have a role in Alzheimer’s disease?

63. Why women experience Alzheimer’s disease differently from men

64. Alzheimer’s disease: highlights from research

65. The unusual genetic inheritance that could change Alzheimer’s treatment

66. Faster, cheaper, better: the rise of blood tests for Alzheimer’s

67. Reframe perspectives on Alzheimer’s disease

68. Within dead branches

69. Don’t believe the hype — quantum tech can’t yet solve real-world problems

70. Science on our sleeves: the research that inspires our tattoos

71. First global pandemic treaty agreed — without the US

72. Roses are red — but their ancestors were yellow

73. Daily briefing: Leaked documents reveal the next science funding on Trump’s chopping block

74. You’re only human: a six-step strategy to surviving your PhD

75. Print, melt, repeat: 3D-printing formula yields sturdy objects time after time

76. Richard Fortey obituary: palaeontologist, author and TV presenter who traced continents through fossils

77. High time to tackle drug-resistant fungal infections

78. Scientists must regain trust

79. Lung signals drive cancer-associated blood clots

80. Twenty years of genome-wide association studies

81. Early air-pollution activists fight against city smoke

82. Pig livers for people: US regulator greenlights first safety trial

83. Should I return to my home country after my PhD abroad?

84. The fight to keep big tech in check: digital researchers are in ‘David and Goliath’ battle

85. Africa CDC must become financially independent

86. Discussions of technologies’ societal impacts are still too limited

87. Ensuring that conferences are inclusive requires diverse organizers

88. Daily briefing: Five lawsuits have been filed in response to NIH cuts — what now?

89. Exclusive: the most-cited papers of the twenty-first century

90. These are the most-cited research papers of all time

91. Science’s golden oldies: the decades-old research papers still heavily cited today

92. Five key climate and space projects on Trump’s chopping block

93. AI-boosted cameras help blind people to navigate

94. Prdm16-dependent antigen-presenting cells induce tolerance to gut antigens

95. Dear US researchers: break the outrage addiction. I survived the besieging of science. So can you

96. Radical approach to shrink particle colliders gains momentum

97. Understanding bones from the remote wilderness of Wyoming

98. How a ‘boring administrative task’ transformed my PhD career

99. How the United States became a science superpower — and how quickly it could crumble

100. Five years on: how Brexit changed three scientists’ careers

101. Daily briefing: Mysterious Taiwan fossil is Denisovan

102. ‘I’m touching space’: the fascinating insights meteorites can bring us

103. The dangerous fantasies driving the quest for super-intelligent AI

104. NIH cuts triggered a host of lawsuits: Nature’s guide to what’s next

105. Liquids in a glass recover a graceful shape even after being shaken

106. Mystery of medieval manuscripts revealed by ancient DNA

107. Author Correction: Sulfide-rich continental roots at cratonic margins formed by carbonated melts

108. Daily briefing: Dogs have a serious environmental impact — but owners can mitigate it

109. How Trump 2.0 is slashing NIH-backed research — in charts

110. Mysterious human fossil found in Taiwan was a Denisovan

111. Physicists narrow down neutrino’s mysterious mass

112. Allergic reactions flare in the gut after cuts to the skin, mouse research shows

113. ‘Mind blowing’: quantum computer untangles the mathematics of knots

114. Top quarks spotted at mega-detector could reveal clues to early Universe

115. Can peer-reviewed podcasts fast-track science?

116. Daily briefing: Tonka bean trees survive lightning strikes that kill their competitors

117. Data centres will use twice as much energy by 2030 — driven by AI

118. Brain cells given an ‘invisibility cloak’ fix Parkinson’s symptoms in rats

119. These 4,200-year-old cymbals show music’s far-reaching power

120. Will AI improve your life? Here’s what 4,000 researchers think

121. Biggest brain map ever details huge number of neurons and their activity

122. DNA-guided transcription factor interactions extend human gene regulatory code

123. What makes us human? Milestone ape genomes promise clues

124. Skin wound healing measured remotely through molecular flux

125. Why it’s time the United Nations is led by a woman

126. Jurassic fossil reveals the origin of parasitic thorny-headed worms

127. A mental-health crisis plagues PhDs — these evidence-led initiatives offer help

128. Chronic stress drives depression by disrupting cellular housekeeping

129. A map of neural signals and circuits traces the logic of brain computation

130. Complete ape genomes offer a close-up view of human evolution

131. A wetter ancient Arabia could have enabled easier intercontinental species dispersal

132. Photonic chips provide a processing boost for AI

133. Docking stations in porous crystals unlock elusive molecular structures

134. Cancer vulnerabilities exposed by finding interactions among DNA repair factors

135. Airborne microplastics enter plant leaves and end up in our food

136. Hunter-gatherers journeyed by sea to Malta

137. Timing and trajectory of BCR::ABL1-driven chronic myeloid leukaemia

138. Functional connectomics reveals general wiring rule in mouse visual cortex

139. Spatial multi-omics reveals cell-type-specific nuclear compartments

140. An integrated large-scale photonic accelerator with ultralow latency

141. Towards conversational diagnostic artificial intelligence

142. Supramolecular docking structure determination of alkyl-bearing molecules

143. Multimodal cell maps as a foundation for structural and functional genomics

144. Intersectional analysis for science and technology

145. Recurrent humid phases in Arabia over the past 8 million years

146. Universal photonic artificial intelligence acceleration

147. Stress dynamically modulates neuronal autophagy to gate depression onset

148. Evidence of star cluster migration and merger in dwarf galaxies

149. A Jurassic acanthocephalan illuminates the origin of thorny-headed worms

150. Functional connectomics spanning multiple areas of mouse visual cortex

151. Translational genomics of osteoarthritis in 1,962,069 individuals

152. Small molecules restore mutant mitochondrial DNA polymerase activity

153. Water abundance in the lunar farside mantle

154. Inhibitory specificity from a connectomic census of mouse visual cortex

155. Transforming ceria into 2D clusters enhances catalytic activity

156. Goal-specific hippocampal inhibition gates learning

157. Complete sequencing of ape genomes

158. NEURD offers automated proofreading and feature extraction for connectomics

159. Hunter-gatherer sea voyages extended to remotest Mediterranean islands

160. Reprogramming site-specific retrotransposon activity to new DNA sites

161. A non-contact wearable device for monitoring epidermal molecular flux

162. Giant electrocaloric effect in high-polar-entropy perovskite oxides

163. Seismic imaging of a basaltic Lesser Antilles slab from ancient tectonics

164. Comprehensive interrogation of synthetic lethality in the DNA damage response

165. Perisomatic ultrastructure efficiently classifies cells in mouse cortex

166. Human assembloid model of the ascending neural sensory pathway

167. Phenotypic complexities of rare heterozygous neurexin-1 deletions

168. Leaf absorption contributes to accumulation of microplastics in plants

169. Foundation model of neural activity predicts response to new stimulus types

170. Swinging lever mechanism of myosin directly shown by time-resolved cryo-EM

171. Active energy compression of a laser-plasma electron beam

172. Immune checkpoint TIM-3 regulates microglia and Alzheimer’s disease

173. Ultra-broadband optical amplification using nonlinear integrated waveguides

174. Connectomics of predicted Sst transcriptomic types in mouse visual cortex

175. Towards accurate differential diagnosis with large language models

176. Long-awaited ape genomes give new insights into their evolution — and ours

177. The great brain clearance and dementia debate

178. Losing weight through better sleep

179. Sleep is essential — researchers are trying to work out why

180. The life aquatic: this board game lets you dip into marine ecology

181. Research round-up: sleep

182. New treatments to put insomnia to bed

183. The infuriating, expensive road to a good night’s sleep

184. Unlocking the secrets of sleep

185. Relics

186. How do I explain the publication gap I ended up with after a hostile manager?

187. Microbial warfare brought us CRISPR. What big breakthroughs could be next?

188. NSF slashes prestigious PhD fellowship awards by half

189. Tiger turnaround as populations grow in India

190. Does US science have a future in Antarctica? Trump cuts threaten to cancel fieldwork and more

191. A Nd@C82-polymer interface for efficient and stable perovskite solar cells

192. Asilomar conference took courage and foresight — today, inclusivity would also be crucial

193. An animal source of mpox emerges — and it’s a squirrel

194. Cannabis studies were informing fundamental neuroscience in the 1970s

195. ‘Now is not the time for despair’ — how scientists can take a stand against political interference

196. Cells are swapping their mitochondria. What does this mean for our health?

197. Norway set to scrap mandatory language training for foreign postdocs and PhD students

198. Science’s big problem is a loss of influence, not a loss of trust

199. Countries must consider their global footprint when using natural resources

200. Europe needs to step up on epidemic preparedness

201. Europe must grasp chance to become a scientific powerhouse

202. The US is against the world on sustainable development

203. Daily briefing: The physicist behind baseball’s new ‘torpedo’ bat

204. 154 million lives and counting: 5 charts reveal the power of vaccines

205. Creating an ‘all comers’ research group in quantitative history

206. Long COVID activists fought Trump team’s research cuts and won ― for now

207. Daily briefing: This brain structure filters which thoughts we become aware of

208. Studying seabirds with a cactus as a research assistant

209. Where do proteins go in cells? Next-generation methods map the molecules’ hidden lives

210. AI for research: the ultimate guide to choosing the right tool

211. From Hippocrates to COVID-19: the scientific fight to prove diseases can be airborne

212. AI race in 2025 is tighter than ever before

213. Why more AI researchers should collaborate with governments

214. Author Correction: Recapitulation of premature ageing with iPSCs from Hutchinson–Gilford progeria syndrome

215. Why an overreliance on AI-driven modelling is bad for science

216. Obesity-drug pioneers and 13,508 physicists win US3-million Breakthrough Prizes

217. International PhD students make emergency plans in fear of US immigration raids

218. Neck deep in overdiagnosis: Books in brief

219. Trump team removes senior NIH chiefs in shock move

220. Revealed: where rare and giant starfish hide from an enigmatic killer

221. Author Correction: Record sea surface temperature jump in 2023–2024 unlikely but not unexpected

222. Tariffs hit science labs: Trump levies raise cost of supplies

223. Daily briefing: Drug makes people’s blood poisonous to mosquitoes

224. Daily briefing: Mass layoffs across US health agencies

225. Author Correction: Traversable wormhole dynamics on a quantum processor

226. Exclusive: Trump White House directs NIH to study ‘regret’ after transgender people transition

227. How does the brain control consciousness? This deep-brain structure

228. Take Nature’s poll: How will Trump’s policies affect US science?

229. Journal targeted by paper mill still grappling with the aftermath years later

230. Solar cells made of Moon dust could power up a lunar base

231. Hidden states and dynamics of fractional fillings in twisted MoTe2 bilayers

232. Strategic atom replacement enables regiocontrol in pyrazole alkylation

233. Intriguing features of the interface between water and oil droplets uncovered

234. From bench to bread: how science can enhance your hobbies

235. Could the shingles vaccine help to prevent dementia?

236. Rare ancient DNA from Sahara opens a window on the region’s verdant past

237. The neurons that mediate a psychedelic’s long-term antidepressive effects

238. AI masters Minecraft: DeepMind program finds diamonds without being taught

239. Light wins uphill battle to solve enduring problem in organic synthesis

240. Sunflower ‘virgin births’ enable accelerated crop breeding

241. Revealed: first DNA profiles of ancient people who roamed a lush Sahara

242. Ancient DNA from the Green Sahara reveals ancestral North African lineage

243. Acoustic modes in M67 cluster stars trace deepening convective envelopes

244. The RAD52 double-ring remodels replication forks restricting fork reversal

245. Haploid facultative parthenogenesis in sunflower sexual reproduction

246. Global impoverishment of natural vegetation revealed by dark diversity

247. A neural mechanism for learning from delayed postingestive feedback

248. Clinically relevant clot resolution via a thromboinflammation-on-a-chip

249. Psilocybin’s lasting action requires pyramidal cell types and 5-HT2A receptors

250. A RISC-V 32-bit microprocessor based on two-dimensional semiconductors

251. Millimetre-scale bioresorbable optoelectronic systems for electrotherapy

252. Metal–support frontier orbital interactions in single-atom catalysis

253. Formation and composition of Earth’s Hadean protocrust

254. Near-field photon entanglement in total angular momentum

255. Bifidobacteria support optimal infant vaccine responses

256. Mastering diverse control tasks through world models

257. A natural experiment on the effect of herpes zoster vaccination on dementia

258. Photoinduced copper-catalysed deracemization of alkyl halides

259. World’s tiniest pacemaker could revolutionize heart surgery

260. Unicorn slippers in space

261. A toolkit for seeing how the fly brain’s visual system works

262. Do smartphones and social media really harm teens’ mental health?

263. Are screens harming teens? What scientists can do to find answers

264. What if human blood were toxic to mosquitoes? A drug can make it so

265. El Niños that linger are becoming less of a rarity

266. ‘One of the darkest days’: NIH purges agency leadership amid mass layoffs

267. CERN releases detailed plans for supercollider — but no hints about funding

268. Author Correction: Isoprene nitrates drive new particle formation in Amazon’s upper troposphere

269. How Europe aims to woo US scientists and protect academic freedom

270. Deadly Myanmar earthquake was likely a rare rupture, scientists say

271. A brain drain would impoverish the United States and diminish world science

272. Author Correction: Controlled patterning of crystalline domains by frontal polymerization

273. How seahorses and pipefish inspired the design of a boat propeller

274. Daily briefing: What happens when you pay peer reviewers?

275. Daily briefing: Women’s work is missing from the scientific literature

276. Superpowers want to control critical mineral supplies — local communities need a stronger say

277. How to get rid of toxic ‘forever chemical’ pollution

278. Action needed to mitigate effects of slashing USAID

279. The global scientific community must keep studying LGBT health

280. China has already taken steps to reduce retractions of papers from its hospitals

281. Minerals will shape future geopolitical order

282. Big cuts to US AIDS prevention feared as NIH axes HIV research grants

283. Incredible close-up of colourful crab spiders — March’s best science images

284. Brain implant translates thoughts to speech in an instant

285. 23andMe plans to sell its huge genetic database: could science benefit?

286. Deep dive: How I use robots to survey coral reefs

287. Style over substance? What birds’ mating behaviours reveal about sexual selection

288. Six roadblocks to net zero — and how to get around them

289. These US labs risk imminent closure after Trump cuts

290. The best foods for healthy ageing ― and the worst

291. Publishers trial paying peer reviewers — what did they find?

292. Audio long read: How quickly are you ageing? What molecular ‘clocks’ can tell you about your health

293. Daily briefing: Pregnancy’s true toll on the body

294. Daily briefing: Why RNA hasn’t yet had its ‘AlphaFold’ moment

295. Can trauma from violence be genetically inherited? Scientists debate Syria refugee study

296. Showing ‘ability’ in ‘disability’ — how I mastered interviews while using a wheelchair

297. Trump’s bid for Greenland threatens to destabilize Arctic research

298. How Trump is following Project 2025’s radical roadmap to defund science

299. ‘Open source’ AI isn’t truly open — here’s how researchers can reclaim the term

300. 75% of US scientists who answered Nature poll consider leaving