1. Volunteer scientists work ‘nights and weekends’ to guide vaccine advice in US

2. Wonder, empathy, life: why we called our pregnancy-diagnostic company Mirvie

3. Connecting the dots: I trace the history of the East Kolkata Wetlands

4. Medicine Nobel goes to scientists who revealed secrets of immune system ‘regulation’

5. The cutting-edge medical approaches that could transform ageing

6. Jane Goodall obituary: pioneer primatologist who inspired generations of scientists

7. 27 things we wish we’d known when we started our PhDs

8. Daily briefing: The Nobel prizes’ most prestigious rivals

9. From fossil fuels to ‘green capitalism’: the dilemmas of a just energy transition

10. Will AI ever win its own Nobel? Some predict a prize-worthy science discovery soon

11. A scientist’s guide to AI agents — how could they help your research?

12. Creative hobbies could slow brain ageing at the molecular level

13. ‘Rogue’ planet is fastest-growing ever observed

14. Weaponizing uncertainty in science and in public health puts people in harm’s way

15. First human transplant of kidney modified to have ‘universal’ blood type

16. Author Correction: Ribonucleotide incorporation into mitochondrial DNA drives inflammation

17. These science prizes want to rival the Nobels: how do they compare?

18. Marcus kinetics control singlet and triplet oxygen evolving from superoxide

19. The child of humanity becomes the mother of all

20. AI has designed thousands of potential antibiotics. Will any work?

21. Violin therapy: Books in brief

22. Daily briefing: ‘A messenger of hope’ — Jane Goodall’s impact on science

23. These alien planets are astronomers’ favourites: here’s why

24. Biothreat hunters catch dangerous DNA before it gets made

25. Scooped by a cupcake business: why we called our green-cement company Sublime Systems

26. Author Correction: EBI2 augments Tfh cell fate by promoting interaction with IL-2-quenching dendritic cells

27. Research assessment: a round-up for early-career researchers

28. Publisher Correction: Multimodal cell maps as a foundation for structural and functional genomics

29. Keep, lose, add: a checklist for plotting your next career move in science

30. Memorable, distinctive, not too ‘sciencey’: why we named our biotech firm Anocca

31. Exclusive: ex-CDC director talks about why she was fired

32. Model organism databases face budget cuts and closures

33. Jane Goodall’s legacy: three ways she changed science

34. Daily briefing: Fireworks in space — the month’s best science images

35. This US government shutdown is different: what it means for science

36. DNA circuits store data — with heat as their power source

37. Early- and late-diagnosed autism are genetically distinct

38. Parachutes inspired by the Japanese art of kirigami

39. Bacteria use a decoy defence molecule to set a trap for viruses

40. Ancient viral DNA in the human genome shapes early development

41. Quantum correlations enhance the sensitivity of room-temperature sensors

42. Features of autism can affect age of diagnosis – and so can genes

43. Machine learning matches enzymes with molecular substrates

44. Mix-and-match fossils tell the tale of snake and lizard evolution

45. A pathway that controls conversion of the amino acid cysteine into a cholesterol regulator

46. Elaborate machinery for inserting proteins into the outer membrane of bacteria

47. Evolution of drug-resistant ovarian-cancer clones tracked in patients

48. End GDP mania: how the world should really measure prosperity

49. Spin squeezing in an ensemble of nitrogen–vacancy centres in diamond

50. Autoimmune response to C9orf72 protein in amyotrophic lateral sclerosis

51. Long-distance remote epitaxy

52. A miniature CRISPR–Cas10 enzyme confers immunity by inhibitory signalling

53. The Panoptes system uses decoy cyclic nucleotides to defend against phage

54. A human-specific regulatory mechanism revealed in a pre-implantation model

55. Doughnut of social and planetary boundaries monitors a world out of balance

56. Mosaic anatomy in an early fossil squamate

57. Connecting chemical and protein sequence space to predict biocatalytic reactions

58. Tracking clonal evolution during treatment in ovarian cancer using cell-free DNA

59. Polygenic and developmental profiles of autism differ by age at diagnosis

60. Monoclonal antibodies protect against pandrug-resistant Klebsiella pneumoniae

61. Heat-rechargeable computation in DNA logic circuits and neural networks

62. Signal amplification in a solid-state sensor through asymmetric many-body echo

63. A new paradigm for outer membrane protein biogenesis in the Bacteroidota

64. Dietary cysteine enhances intestinal stemness via CD8 T cell-derived IL-22

65. Efferocytic remodelling of pancreatic islet macrophages by limited β-cell death

66. Kirigami-inspired parachutes with programmable reconfiguration

67. Proteotoxic stress response drives T cell exhaustion and immune evasion

68. These laser-cut discs turn into super precise parachutes

69. Ancient viral DNA helps human embryos develop

70. Author Correction: Prophylactic TNF blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy

71. HELIOS: a microcosm of Asian health with global reach

72. China’s research hospitals push for prominence

73. A guide to the Nature Index

74. Uniting Africa’s longitudinal cohorts

75. Fixing the imbalance in cancer rates between Black and white women

76. Hospitals have long been key for research, now their influence is broadening

77. How research hospitals are meeting the world’s health challenges

78. The devourer of trust

79. AI uses medical records to accurately predict onset of disease 20 years into the future

80. Gut microbiota keeps watch over future egg cells

81. Will your study change the world? This AI tool predicts the impact of your research

82. Six journal rejections and a major rethink: why I’m happy to admit to my research failures, and you should too

83. Trees of the Amazon are becoming even mightier

84. Daily briefing: Tiny charged bubbles of methane could explain will-o’-the-wisps

85. AI is dreaming up millions of new materials. Are they any good?

86. Saharan dust on the wind linked to hail in Europe

87. Death of a star leaves a legacy for exoplanets

88. Author Correction: Crystal structure of heliorhodopsin

89. See space fireworks and lightning spaghetti — September’s best science images

90. Early efforts to understand the processes underlying bird migration

91. Trust in the sea-bed mining authority is fragile — here’s how to change that

92. How to get the best night’s sleep: what the science says

93. Technology leaders should ‘pay back’ society to support the common good

94. Add a ‘speculation box’ to research papers

95. Make cities more walkable, in the real world and in virtual reality

96. AI tools could reduce the appeal of predatory journals

97. India and Pakistan share flood risks and must combine solutions

98. Daily briefing: Rookie researchers boost disruptive science

99. NIH races to spend its 2025 grant money — but fewer projects win funding

100. Daily briefing: Universities made the modern world — now they must survive it

101. How to find the papers you need to read — and avoid the ones you don’t

102. Power and profit drive what we eat: here’s why the food system needs a revolution

103. Rookie scientists make research teams more innovative

104. Public trust in science has declined since COVID — virologists need to unite around safety standards

105. How money, politics and technology are redefining the PhD experience in 2025

106. Little urchins, mischievous molluscs: my life as a sea champion

107. Author Correction: Selenium-alloyed tellurium oxide for amorphous p-channel transistors

108. Publisher Correction: Psilocybin’s lasting action requires pyramidal cell types and 5-HT2A receptors

109. China pledges to cut emissions by 2035: what does that mean for the climate?

110. Audio long read: Autism is on the rise — what’s really behind the increase?

111. How autism research quietly advanced this week despite talk of Tyenol link

112. Mitochondria expel tainted DNA — spurring age-related inflammation

113. What happens if pregnant women stop taking Tylenol?

114. Daily briefing: How to live to 117

115. Common air pollutant has a secret weapon: bacterial toxins

116. Swapping old immune cells in the brain with fresh ones could treat disease

117. How passage through the Milky Way’s spiral arms altered our planet

118. Python, the movie! The programming language’s origin story comes to the silver screen

119. Huntington’s disease treated for first time using gene therapy

120. Mammoth challenge: why we called our de-extinction company Colossal Biosciences

121. Big mother whales have more daughters than sons

122. US serial killer case opens door to using cutting-edge DNA data in courts

123. Retractions can reshape scientists’ careers in unexpected ways

124. When life gets in the way of your meticulously-planned career in science

125. Why is autism really on the rise? What the science says

126. Daily briefing: ‘Thinky think before grabby grab’ — lab tips for science success

127. Trump’s 100K visa fee for foreign talent: how will it affect researchers?

128. It’s not wokeness — it’s human rights

129. Arousal reframed as an organism‑wide dynamic system

130. How a dangerous tick-borne virus sneaks into the brain

131. Machine learning reveals potential consequences of cuts to US research

132. What research might be lost after the NIH’s cuts? Nature trained a bot to find out

133. Arousal as a universal embedding for spatiotemporal brain dynamics

134. Jazzy jaw joints: evolutionary fine-tuning reveals unexpected bone connections in ancient predecessors of mammals

135. How universities came to be — and why they are in trouble now

136. A common chromosome fusion in humans explained

137. The great university shake-up: four charts show how global higher education is changing

138. Electrostatic-based transfer keeps 2D materials ultra-clean

139. She lived to 117: what her genes and lifestyle tell us about longevity

140. How a tick-borne virus enters human cells

141. A drug–diet combination could improve childhood cancer treatment

142. Universities are — and must continue to be — a force for good

143. Using short synthetic nucleic acids to probe genes in viruses that infect bacteria

144. The future of universities: a Nature special report

145. No lectures, exams, essays: inside a twenty-first-century university

146. Boosting immune cells to combat cancer using CRISPR engineering and large-scale in vivo testing

147. Climate change is reshaping fish communities in the United States

148. Universities under fire must harness more of the financial value they create

149. Robotic system takes chemistry into hyperspace

150. Universities must move with the times: how six scholars tackle AI, mental health and more

151. Engineered enzymes can suppress genome-editing errors

152. Low-overhead transversal fault tolerance for universal quantum computation

153. The Biodiversity Cell Atlas: mapping the tree of life at cellular resolution

154. Electrostatic-repulsion-based transfer of van der Waals materials

155. In vivo CRISPR screens identify modifiers of CAR T cell function in myeloma

156. Protecting double Holliday junctions ensures crossing over during meiosis

157. The formation and propagation of human Robertsonian chromosomes

158. A haplotype-based evolutionary history of barley domestication

159. LRP8 is a receptor for tick-borne encephalitis virus

160. Reprogramming neuroblastoma by diet-enhanced polyamine depletion

161. Systematic discovery of CRISPR-boosted CAR T cell immunotherapies

162. Holliday junction–ZMM protein feedback enables meiotic crossover assurance

163. Isothermal solidification for high-entropy alloy synthesis

164. Proximal cooperative aerial manipulation with vertically stacked drones

165. Robot-assisted mapping of chemical reaction hyperspaces and networks

166. Collective homeostasis of condensation-prone proteins via their mRNAs

167. Design of facilitated dissociation enables timing of cytokine signalling

168. Volcanic crisis reveals coupled magma system at Santorini and Kolumbo

169. Diverging fish biodiversity trends in cold and warm rivers and streams

170. Tailoring polymer electrolyte solvation for 600 Wh kg1 lithium batteries

171. Ribonucleotide incorporation into mitochondrial DNA drives inflammation

172. Convergent evolution of diverse jaw joints in mammaliamorphs

173. SPP1 is required for maintaining mesenchymal cell fate in pancreatic cancer

174. Industry-compatible silicon spin-qubit unit cells exceeding 99% fidelity

175. The geoeconomic turn in decarbonization

176. A tweezer array with 6100 highly coherent atomic qubits

177. Tylenol is over 130 years old — why is it still the gold-standard painkiller?

178. Exclusive: RFK Jr cancelled mRNA research — but the US military is still funding it

179. A press release from just before the singularity

180. Daily briefing: No strong evidence backs up Trump’s claims about Tylenol and autism

181. Fighting climate change takes more than data — it needs wonder, love and hope

182. Trump team backs an unproven drug for autism — but does it work?

183. ‘Shake it off’: Taylor Swift’s changing voice shows how our accents evolve

184. It’s a new term: here are 99 lab hacks

185. Nerdy and easy to pronounce: why we chose Apheros as the name for our technology start-up firm

186. Journals infiltrated with ‘copycat’ papers that can be written by AI

187. A multimodal robotic platform for multi-element electrocatalyst discovery

188. Fossil fight: how Raymond Dart countered some unfair criticism

189. How can universities train the skilled workers of tomorrow?

190. The meaning behind the moniker: how to choose a science-company name that delights customers, colleagues and investors

191. Daily briefing: World’s first AI-designed viruses attack antibiotic-resistant bacteria

192. The mini placentas and ovaries revealing the basics of women’s health

193. Ebola outbreak in the DRC: why is it so deadly?

194. Combat the human-made causes of Spain’s wildfires

195. China’s private higher-education sector is at a turning point

196. Long-standing marine reserves need continued support

197. US investment in African food systems will have global benefits

198. Trump links autism and Tylenol: is there any truth to it?

199. The Moon is rusting — thanks to ‘wind’ blown all the way from Earth

200. Is this really the world''s largest mirror? Researchers put it to the test

201. Corpse flowers waft out stinky compounds as fast as landfills do

202. Decoding the redox behaviour of copper in Ullmann-type coupling reactions

203. Gestational diabetes linked to autism in study: what scientists say

204. Real-time molecular recorders expose the inner lives of cells

205. I deeply scan timber to reduce wasting this precious resource

206. What drove the rise of civilizations? A decades-long quest points to warfare

207. Author Correction: Mechanism of BRCA1–BARD1 function in DNA end resection and DNA protection

208. Daily briefing: Device senses silent speech without an invasive brain implant

209. Hotly anticipated US vaccine meeting ends with confusion — and a few decisions

210. Atomic ‘conveyor belt’ boosts power of quantum computer

211. Harvard vs Trump: research funds still mostly frozen despite court win

212. Apocalypse then: how cataclysms shaped human societies

213. Daily briefing: AI model can predict your risk of diseases years before you might get them

214. Author Correction: Clonal dynamics and somatic evolution of haematopoiesis in mouse

215. Publisher Correction: Functional synapses between neurons and small cell lung cancer

216. A Chinese AI tool can manage chronic disease — could it revolutionize health care?

217. World''s first AI-designed viruses a step towards AI-generated life

218. Reviving the past and designing the future: Books in brief

219. How a mentoring connection boosted my ambitions for a science career

220. Tipsy bats and perfect pasta: Ig Nobels celebrate ‘improbable’ research

221. Soft robot steers itself down the human airway

222. The ‘near-telepathic’ device that puts AI in your head

223. Wildfire smoke exposure and mortality burden in the US under climate change

224. Author Correction: A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome

225. Global warming amplifies wildfire health burden and reshapes inequality

226. Can AI chatbots trigger psychosis? What the science says

227. Two tools to help you achieve career success in science

228. Daily briefing: Can AI help us talk to animals?

229. Three ways ex-CDC chief says that Trump team is sidelining science

230. Wired for growth: neuron–tumour signalling in the lung and brain increases growth of a hard-to-treat cancer

231. Will the public support basic science? A new non-profit aims to find out

232. Years of hits to the head prime the brain for decline

233. Earth’s atmosphere took two billion years to become fully oxygenated

234. Bioelectronic implants built from rolled-up stretchy circuits

235. Pharmaceutical giants pull out of UK: why it matters for global science

236. Bespoke 3D printing adapted to features mapped using computer vision

237. Secrets of DeepSeek AI model revealed in landmark paper

238. AI can learn to show its workings through trial and error

239. People are more likely to cheat when they delegate tasks to AI

240. Bring us your LLMs: why peer review is good for AI models

241. Which diseases will you have in 20 years? This AI makes accurate predictions

242. A photonic chip enables ultrabroadband wireless communication

243. A surprising way to make heat in an unexpected part of fat cells

244. Caribbean coral reefs are threatened by rising seas

245. A domed pachycephalosaur from the early Cretaceous of Mongolia

246. Peroxisomal metabolism of branched fatty acids regulates energy homeostasis

247. Co-option of an ancestral cloacal regulatory landscape during digit evolution

248. Learning the natural history of human disease with generative transformers

249. Delegation to artificial intelligence can increase dishonest behaviour

250. Structural basis for mTORC1 activation on the lysosomal membrane

251. DeepSeek-R1 incentivizes reasoning in LLMs through reinforcement learning

252. Reduced Atlantic reef growth past 2 C warming amplifies sea-level impacts

253. High-density soft bioelectronic fibres for multimodal sensing and stimulation

254. A room temperature rechargeable all-solid-state hydride ion battery

255. Myeloperoxidase transforms chromatin into neutrophil extracellular traps

256. Selective presynaptic inhibition of leg proprioception in behaving Drosophila

257. Covariation MS uncovers a protein that controls cysteine catabolism

258. Stratified wind from a super-Eddington X-ray binary is slower than expected

259. Atomic-scale imaging of frequency-dependent phonon anisotropy

260. A movable long-term implantable soft microfibre for dynamic bioelectronics

261. Transitions in dynamical regime and neural mode during perceptual decisions

262. Toughened self-assembled monolayers for durable perovskite solar cells

263. Addressing the safety of next-generation batteries

264. Engineered prime editors with minimal genomic errors

265. Repeated head trauma causes neuron loss and inflammation in young athletes

266. Analogue speech recognition based on physical computing

267. CRISPR activation for SCN2A-related neurodevelopmental disorders

268. A neuronal architecture underlying autonomic dysreflexia

269. Basal cell of origin resolves neuroendocrine–tuft lineage plasticity in cancer

270. This AI tool predicts your risk of 1,000 diseases — by looking at your medical records

271. A plant-forward menu is linked to lower diabetes risk

272. Can We Fix America’s Dementia Care Crisis before It’s Too Late?

273. Alzheimer’s Drugs Are Finally Tackling the Disease Itself. Here’s How

274. The Hidden Link between Racism and Alzheimer’s Risk

275. The Vexing Promise of New Blood Tests for Alzheimer’s

276. Can Diet and Exercise Really Prevent Alzheimer’s?

277. Controversial New Alzheimer’s Drugs Offer Hope—But at a High Cost

278. New Hope in Alzheimer’s Research

279. My career switch from psychologist to open-science advocate

280. The parable of the doors

281. Daily briefing: A ‘time crystal’ made visible to the naked eye

282. AI is helping to decode animals’ speech. Will it also let us talk with them?

283. Mysterious changes near Earth’s core revealed by satellites in space

284. Rare comet photobombs telescope’s view of the cosmos

285. Delta-type glutamate receptors are ligand-gated ion channels

286. Make trains great again — for the sake of people and the planet

287. Publisher Correction: TCF1 and LEF1 promote B-1a cell homeostasis and regulatory function

288. ‘Revolutionary’ AI tools rescue old weather data to improve climate models

289. Mysterious mass deaths of an extinct giant deer

290. Gone with the wind: deciphering how dandelions drive seed dispersal

291. Equity in science is a beautiful lie — and I’m done pretending

292. How billions of hacked mosquitoes and a vaccine could beat the deadly dengue virus

293. How did assaults on science become the norm — and what can we do?

294. Coordinate to combat Pakistan’s climate-driven disasters

295. A population plunge could help to mitigate the global biodiversity crisis

296. Impoundment of funds endangers US investment in science and medical research

297. Fertility declines are no cause for concern, history shows

298. Daily briefing: What’s next for gravitational-wave detectors?

299. Ssmoke-dried mummies pre-date Egypt’s embalmed bodies

300. Mirror of the unknown: should research on mirror-image molecular biology be stopped?