1. The Indian Ocean disaster is a climate tragedy — and needs more attention

2. AI is saving time and money in research — but at what cost?

3. These are a few of my favourite sounds: Books in brief

4. Fate of hepatitis B vaccine for US babies hangs in the balance

5. DeepSeek’s self-correcting AI model aces tough maths proofs

6. AI chatbots can persuade voters to change their minds

7. AI chatbots can sway voters with remarkable ease — is it time to worry?

8. China’s scientific clout is growing as US influence wanes: the data show how

9. Persuading voters using human–artificial intelligence dialogues

10. Aluminium is crucial to vaccines — and safe. Why are US advisers debating it?

11. Author Correction: Activity of caspase-8 determines plasticity between cell death pathways

12. Experimental vaccine prevents deadly allergic reactions in mice

13. Satellite swarms set to photobomb more than 95% of some telescopes’ images

14. Still no sign of hypothetical sterile-neutrino particle

15. Quarks in ‘exotic’ quartets prefer to stick together

16. Even in space, telescopes can’t escape photobombers

17. Order in which cancer-driving mutations occur affects the chance of tumour development

18. Primate embryo model leaps across developmental boundaries

19. A glasses-free 3D display uses AI to direct images straight to the viewer’s eyes

20. Decay of driver mutations shapes the landscape of intestinal transformation

21. Architecture of the neutrophil compartment

22. Homo sapiens-specific evolution unveiled by ancient southern African genomes

23. Viral RNA blocks circularization to evade host codon usage control

24. Search for light sterile neutrinos with two neutrino beams at MicroBooNE

25. Video-call glitches trigger uncanniness and harm consequential life outcomes

26. Built environment disparities are amplified during extreme weather recovery

27. Computational enzyme design by catalytic motif scaffolding

28. Satellite megaconstellations will threaten space-based astronomy

29. Determination of the spin and parity of all-charm tetraquarks

30. The Microflora Danica atlas of Danish environmental microbiomes

31. TSC tunes progenitor balance and upper-layer neuron generation in neocortex

32. Dated gene duplications elucidate the evolutionary assembly of eukaryotes

33. Modelling late gastrulation in stem cell-derived monkey embryo models

34. Whole-genome landscapes of 1,364 breast cancers

35. Sterile-neutrino search based on 259 days of KATRIN data

36. A place-based assessment of biodiversity intactness in sub-Saharan Africa

37. Computational design of metallohydrolases

38. Photobombing satellites could ruin the night sky for space telescopes

39. Building mentally healthy cities with neuroscience

40. How cities can keep their cool

41. Cities aren’t built for women — it’s time to change that

42. Wooden skyscrapers point the way to more sustainable cities

43. Geothermal networks let cities warm and cool as one

44. Cities are embracing nature for flood defence

45. Data drive city transportation forwards

46. Darleane C. Hoffman obituary: chemist who expanded the periodic table

47. Growing cities face mounting challenges

48. A bothy among the stars

49. Author Correction: Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis

50. China accounts for more than half of leading output in the applied sciences

51. ‘Anyone hired a student before?’ How a group of novice lab leaders are supporting each other

52. Author Correction: Seismic detection of a 600-km solid inner core in Mars

53. AI reviewers are here — we are not ready

54. Retraction Note: The economic commitment of climate change

55. The ‘silent’ brain cells that shape our behaviour, memory and health

56. This is the world’s largest spider web — November’s best science images

57. Practical alternative to explosive reaction will improve lab safety

58. Bulk superconductivity up to 96 K in pressurized nickelate single crystals

59. Don’t downplay problems of bullying and harassment in academia

60. Towns lag behind the switch to standard time

61. Author Correction: The first-principles phase diagram of monolayer nanoconfined water

62. Great science happens in great teams — research assessments must try to capture that

63. ‘Fire amoeba’ survives in hotter conditions than any other complex cell

64. Author Correction: Video‐rate tunable colour electronic paper with human resolution

65. Why universities need to radically rethink exams in the age of AI

66. Alternatives to animal research are not inherently more ethical

67. Drinking water is at risk during warfare — better protections are needed

68. Ease the EU postdoc job market with better routes to innovation

69. Memes reveal threats to graduate-student mental health

70. Will blockbuster obesity drugs revolutionize addiction treatment?

71. Antibodies and T cells join forces for sustained HIV remission

72. Correlates of HIV-1 control after combination immunotherapy

73. Sustained HIV-1 remission after heterozygous CCR5Δ32 stem cell transplantation

74. CD8 T cell stemness precedes post-intervention control of HIV viremia

75. Climbing through the silver mine: my work as a geologist

76. Spineless creatures, possibly the world’s oldest beer receipt and more: 2025’s best Books in brief

77. Nature at its weirdest: what metamorphosis reveals about science and ourselves

78. David Baltimore obituary: virologist whose enzyme discovery transformed understanding of cancer and HIV/AIDS

79. China wants to lead the world on AI regulation — will the plan work?

80. Cooking up a storm of air pollution

81. The mystery of emerald green — cracked

82. AI finds signs of life in ancient rocks

83. Editorial Expression of Concern: Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells

84. Audio long read: Faulty mitochondria cause deadly diseases — fixing them is about to get a lot easier

85. Author Correction: Diversity-oriented synthesis yields novel multistage antimalarial inhibitors

86. Author Correction: Evidence for improved DNA repair in the long-lived bowhead whale

87. Laser cooling traps more antimatter atoms than ever before

88. A structured system: the secrets of Germany’s scientific reputation

89. Large language models are biased — local initiatives are fighting for change

90. Author Correction: Nasal delivery of an IgM offers broad protection from SARS-CoV-2 variants

91. Major AI conference flooded with peer-reviews written fully by AI

92. Author Correction: Inhibiting membrane rupture with NINJ1 antibodies limits tissue injury

93. Author Correction: Matrix viscoelasticity promotes liver cancer progression in the pre-cirrhotic liver

94. AlphaFold is five years old — these charts show how it revolutionized science

95. Land-use changes threaten the safety net for birds

96. Shape-shifting electrodes tune optical-frequency converter

97. Ancient DNA offers clues about mysterious prehistoric settlement in China

98. Weighing up the wild-meat harvest in Amazonia

99. Is there lightning on Mars?

100. Mystery owner of African hominin foot identified

101. Double whammy: drugs that inhibit kinase enzymes also speed up their disposal

102. A distinctive human genetic lineage persisted in central Argentina for 8,500 years

103. Yarns and fabrics that bend or stiffen under magnetic fields

104. Digging into the mechanisms that underlie soil production

105. Long-read metagenomics reveals phage dynamics in the human gut microbiome

106. Operating two exchange-only qubits in parallel

107. Healthy forests safeguard traditional wild meat food systems in Amazonia

108. Entanglement-enhanced nanoscale single-spin sensing

109. Progressive coevolution of the yeast centromere and kinetochore

110. Detection of triboelectric discharges during dust events on Mars

111. Glasses-free 3D display with ultrawide viewing range using deep learning

112. Land-use change undermines the stability of avian functional diversity

113. No meta-analytical effect of economic inequality on well-being or mental health

114. Evolution of taste processing shifts dietary preference

115. New finds shed light on diet and locomotion in Australopithecus deyiremeda

116. Ancient DNA from Shimao city records kinship practices in Neolithic China

117. Inhibitors supercharge kinase turnover through native proteolytic circuits

118. Inhibitory PD-1 axis maintains high-avidity stem-like CD8 T cells

119. iHALT unlocks liver functionality as a surrogate secondary lymphoid organ

120. Ethylene modulates cell wall mechanics for root responses to compaction

121. Multi-qubit nanoscale sensing with entanglement as a resource

122. Vicarious body maps bridge vision and touch in the human brain

123. Slipknot-gauged mechanical transmission and robotic operation

124. Building compositional tasks with shared neural subspaces

125. Ferroelectric transistors for low-power NAND flash memory

126. NSD2 targeting reverses plasticity and drug resistance in prostate cancer

127. Thalamocortical transcriptional gates coordinate memory stabilization

128. These ‘programmable’ knots harness physics to make surgical stitches safer

129. This is what lightning on Mars sounds like

130. Trump''s AI ‘Genesis Mission'': what are the risks and opportunities?

131. Author Correction: Photocatalytic low-temperature defluorination of PFASs

132. How to stop the revolving door of German academia

133. The Venus project

134. Why the world must wake up to China’s science leadership

135. ‘They don’t have symptoms’: CAR-T therapies send autoimmune diseases into remission

136. ADHD diagnoses are growing. What’s going on?

137. ‘Anti-woke’ policies blamed for falling attendance at some US conferences

138. We are all mosaics: vast genetic diversity found between cells in a single person

139. Polyclonal origins of human premalignant colorectal lesions

140. What happened at COP30? 4 science take-homes from the climate summit

141. Thirty years of Bose–Einstein condensation

142. World leaders must find the courage to end the fossil-fuel age

143. The ocular microbiome: more than meets the eye

144. Earthquakes, hurricanes and floods: protecting the people who live in hazardous places

145. Author Correction: An asymmetric fission island driven by shell effects in light fragments

146. Author Correction: Spatial fibroblast niches define Crohn’s fistulae

147. Don’t scrap climate COPs, reform them

148. This AI combo could unlock human-level intelligence

149. International environmental treaties cannot be reformed through rational design

150. Universities must help students faced with the death of a supervisor

151. Chile must preserve international science in Antarctica

152. Lack of funding is pushing research in Romania to extinction

153. MAPK-driven epithelial cell plasticity drives colorectal cancer therapeutic resistance

154. A ten-year drive to credit authors for their work — and why there’s still more to do

155. Chasing crayfish and the leeches that live on them

156. The Internet is broken and the inventor of the World Wide Web wants to fix it

157. Why the global economic system should value life on our planet, not exploit it

158. Daily briefing: Where pigeons get their sense of direction

159. What is the future of intelligence? The answer could lie in the story of its evolution

160. Hydrogen fuel isn’t always the green choice

161. Synthetic tongue rates chillies’ heat — and spares human tasters

162. I encourage women to claim their space in astrophysics and beyond

163. Cyberattacks'' harm to universities is growing — and so are their effects on research

164. Of masks and Mayans: Books in brief

165. Psychedelics and immortality: Nature went to a health summit starring RFK and JD Vance

166. How to defuse a time bomb

167. Daily briefing: What happens to science if the ‘AI bubble’ bursts?

168. Daily briefing: Kissing might have evolved 21.5 million years ago

169. Has birds’ mysterious ‘compass’ organ been found at last?

170. The origin of male seahorses’ brood pouch

171. A brain implant that could rival Neuralink''s enters clinical trials

172. Bacterial cooperative weaves sustainable rainbow materials

173. Neanderthal DNA reveals how human faces form

174. Waste not: how researchers harness pee and poo for science

175. Author Correction: A pangenome and pantranscriptome of hexaploid oat

176. How to fix genetic ‘nonsense’: versatile gene-editing tool could tackle a host of diseases

177. Women seem to retract fewer papers than men — but why?

178. Electro-generated excitons for tunable lanthanide electroluminescence

179. Repulsions instruct synaptic partner matching in an olfactory circuit

180. Semantic design of functional de novo genes from a genomic language model

181. Stop the nonsense: genome editing creates potentially therapeutic transfer RNAs

182. Circular DNA has a ticket to ride chromosomes

183. Lanthanides go electric: promising light emitters used in LEDs

184. Tuning into a massive stellar storm on the radio

185. How do genetic association studies rank genes?

186. If the AI bubble bursts, what will it mean for research?

187. Shared and language-specific phonological processing in the human temporal lobe

188. Genetic elements promote retention of extrachromosomal DNA in cancer cells

189. Rare microbial relict sheds light on an ancient eukaryotic supergroup

190. Topological nodal i-wave superconductivity in PtBi2

191. A skin-permeable polymer for non-invasive transdermal insulin delivery

192. Triplets electrically turn on insulating lanthanide-doped nanoparticles

193. Rewiring an olfactory circuit by altering cell-surface combinatorial code

194. Hepatic zonation determines tumorigenic potential of mutant β-catenin

195. Integrator dynamics in the cortico-basal ganglia loop for flexible motor timing

196. Tumour-reactive heterotypic CD8 T cell clusters from clinical samples

197. Structural basis of regulated N-glycosylation at the secretory translocon

198. ZAK activation at the collided ribosome

199. Prime editing-installed suppressor tRNAs for disease-agnostic genome editing

200. Connectivity underlying motor cortex activity during goal-directed behaviour

201. Insulin cream offers needle-free option for diabetes

202. The Asymmetric Synthesis of an Acyclic N-Stereogenic Amine

203. Standing up for Inuit-led research in Canada’s changing Arctic

204. Budget release: Canada courts US researchers and signals wider commitment to science

205. Science on shaky ground: Canadian research shifts in the wake of US cuts

206. The singular proposition of trees

207. South Africa is right to put debt, climate and inequality at the heart of G20

208. Author Correction: AIM2 in regulatory T cells restrains autoimmune diseases

209. Author Correction: A metallic p-wave magnet with commensurate spin helix

210. Daily briefing: This enigmatic figure reveals a common ancient myth

211. Mind-reading devices can now predict preconscious thoughts: is it time to worry?

212. Measles makes a comeback: four charts show where and how

213. The UK must not lose its focus on science and innovation

214. Fall-prevention clinical trial in rural China shows promising results

215. Honouring visionary scientist and Nature’s founder, Norman Lockyer

216. AI has a democracy problem — here’s why

217. Bill Gates’s climate comments are a dangerous distraction

218. Author Correction: Brahma safeguards canalization of cardiac mesoderm differentiation

219. Introducing the j-metric: a true measure of what matters in academia

220. Google DeepMind won a Nobel prize for AI: can it produce the next big breakthrough?

221. Daily briefing: This whale has been spotted alive in the wild for the first time ever

222. Beyond growth — why we need to agree on an alternative to GDP now

223. Nations at COP30 must cancel fossil-fuel concessions to keep the Paris agreement in reach

224. Fishing around offshore wind farms could boost both conservation and green energy

225. Leaders at COP30 should promote solar and wind power over mega-dams

226. Panels of peers are needed to gauge AI’s trustworthiness — experts are not enough

227. How obesity drugs quiet ‘food noise’ in the brain

228. The apple of my eye: How I’ve created a plant-health tracker for farmers in Tanzania

229. On the move: why PhD students study abroad in 2025

230. George Smoot obituary: Charismatic cosmologist who revealed ripples in the Big Bang’s afterglow

231. Why space exploration needs science leadership now — before it’s too late

232. How COVAX raced to protect the world from COVID-19

233. Daily briefing: How ancient humans bred and traded dogs

234. Author Correction: Mechanisms of stretch-mediated skin expansion at single-cell resolution

235. Who will fill the climate-data void left by the Trump administration?

236. Three research stars fighting to protect coastlines

237. Sinking cities: how China is moving subsidence research forward

238. The leading cities in the world for high-quality research in 2024

239. Why coastal megacities should look inland for research collaborations

240. ‘Malicious use is already happening’: machine-learning pioneer on making AI safer

241. The future of AI

242. A Chinese AI model taught itself basic physics — what discoveries could it make?

243. Why I moved my research to China from Germany: a biologist’s experience

244. Spaceport mementos

245. Daily briefing: Greenhouse-gas emissions should peak by 2030, say researchers

246. Volcano mega-eruptions lead to parched times

247. How ancient humans bred and traded the first domestic dogs

248. Tiny robots swim through blood, deliver drugs — and then dissolve

249. James Watson obituary: co-discoverer of DNA’s double helix who reshaped modern biology

250. Pig-organ transplants are often rejected — researchers find a way to stop it

251. CRISPR vs cholesterol: can gene editing prevent heart disease?

252. Physiology and immunology of pig-to-human decedent kidney xenotransplant

253. Multi-omics analysis of a pig-to-human decedent kidney xenotransplant

254. Could China’s cautious new research strategy stifle its science-leadership ambitions?

255. ''Tiny'' AI model beats massive LLMs at logic test

256. The US government shutdown is over: what’s next for scientists

257. Researching sustainable food production, with help from the cows

258. Global greenhouse-gas emissions are still rising: when will they peak?

259. First new type of malaria treatment in decades shows promise against drug resistance

260. Magnetic fibres give this robot a soft grip

261. Can UK science really spawn a 1-trillion company?

262. Metabolite maps reveal spatial gradients in liver and intestinal tissue

263. Official statistics are vastly undercounting deaths from extreme weather

264. Ultrathin films of a 2D polymer provide airtight seal

265. Material system enhances superconducting qubits

266. Extreme rainfall poses the biggest risk to Mumbai’s most vulnerable people

267. SIGLEC12 mediates plasma membrane rupture during necroptotic cell death

268. Convergent genome evolution shaped the emergence of terrestrial animals

269. iPEX enables micrometre-resolution deep spatial proteomics via tissue expansion

270. Radio burst from a stellar coronal mass ejection

271. Viral NblA proteins negatively affect oceanic cyanobacterial photosynthesis

272. GREGoR: accelerating genomics for rare diseases

273. Cytosolic acetyl-coenzyme A is a signalling metabolite to control mitophagy

274. A molecularly impermeable polymer from two-dimensional polyaramids

275. An ancient recombination desert is a speciation supergene in placental mammals

276. Synthesis of enantioenriched atropisomers by biocatalytic deracemization

277. Rare genetic variants confer a high risk of ADHD and implicate neuronal biology

278. Silicon solar cells with hybrid back contacts

279. A universal speed limit for spreading of coherence

280. Photoinduced twist and untwist of moiré superlattices

281. Aligning machine and human visual representations across abstraction levels

282. Mortality impacts of rainfall and sea-level rise in a developing megacity

283. The contribution of rock strength to soil production

284. Florigen activation complex forms via multifaceted assembly in Arabidopsis

285. Spatial fibroblast niches define Crohn’s fistulae

286. Estimation and mapping of the missing heritability of human phenotypes

287. Ecology and spread of the North American H5N1 epizootic

288. In situ structural mechanism of epothilone-B-induced CNS axon regeneration

289. Controlling pyramidal nitrogen chirality by asymmetric organocatalysis

290. Dye or die: bacterium forced to make pigment to stay alive

291. Huge eruption on a distant star confirmed at last

292. Emerging climate impact on carbon sinks in a consolidated carbon budget

293. Olympiad-level formal mathematical reasoning with reinforcement learning

294. Potent neutralization of Marburg virus by a vaccine-elicited antibody

295. Mathematicians put AI model AlphaProof to the test

296. Fossilized technology: Books in brief

297. Three rising stars in ageing research

298. Is ageing a disease? The debate that could reshape medicine

299. Could humans live to 150? Why some researchers think we’re on the cusp of a major longevity breakthrough

300. The future of ageing: science aims to deliver another leap in lifespan