1. HPV vaccine could help to protect the unvaccinated against cervical cancer

2. Gifted dogs learn new words by overhearing humans

3. Climate trends influence transatlantic flight times

4. My PI is not offering any support or guidance on my PhD project, what should I do?

5. How do vaccine cutbacks affect public health? Ask Japan

6. Briefing Chat: Can NASA return rocks from Mars? And why dogs have long ears

7. Daily briefing: Cancer cells stay hidden using stolen mitochondria

8. Humanoid robots step up their game: how useful are the latest droids?

9. PhD students’ taste for risk mirrors their supervisors’

10. A ‘time capsule for cells’ stores the secret experiences of their past

11. Campus protests and civil disobedience: does academia have a problem with activism?

12. Making progress on global health will need high-quality evidence

13. Nationwide genetic screening proves effective at catching disease risk early

14. Daily briefing: Why ‘harmless’ germs can be deadly for some people

15. During the course of my PhD, I’ve been relearning how to rest

16. Why is flu so bad this year? Highly mutated variant offers answers

17. Wolf pup’s stomach yields DNA from one of world’s last surviving woolly rhinos

18. How ageing harms the body’s response to raging infection

19. US science in 2026: five themes that will dominate Trump’s second year

20. Ancient pottery reveals early evidence of mathematical thinking

21. Memories of items and their contexts are encoded by separate groups of human brain cells

22. Biosensors characterize the routes taken by receptors to different active states

23. Genomic clues to the origin of eukaryotic cells

24. Credit in research goes hand in hand with responsibility

25. Ageing rewires the body’s tolerance to infection

26. Mysterious ‘little red dots’ could be black holes in disguise

27. Stretchy organic LED devices with an ‘exciplex’ state are highly efficient

28. LLMs behaving badly: mistrained AI models quickly go off the rails

29. AI tools boost individual scientists but could limit research as a whole

30. Polyamine-dependent metabolic shielding regulates alternative splicing

31. Sub-zero Celsius elastocaloric cooling via low-transition-temperature alloys

32. Artificial intelligence tools expand scientists’ impact but contract science’s focus

33. Predictive coding of reward in the hippocampus

34. An electrically injected solid-state surface acoustic wave phonon laser

35. CFAP20 salvages arrested RNAPII from the path of co-directional replisomes

36. Language model-guided anticipation and discovery of mammalian metabolites

37. Ultra-high-throughput mapping of genetic design space

38. Little red dots as young supermassive black holes in dense ionized cocoons

39. N1-Methylpseudouridine directly modulates translation dynamics

40. The ubiquitin ligase KLHL6 drives resistance to CD8 T cell dysfunction

41. A nowhere-to-hide mechanism ensures complete piRNA-directed DNA methylation

42. Trapping of single atoms in metasurface optical tweezer arrays

43. Enriching African genome representation through the AGenDA project

44. Global subsidence of river deltas

45. Disease tolerance and infection pathogenesis age-related tradeoffs in mice

46. Ligand-specific activation trajectories dictate GPCR signalling in cells

47. 3D-printed low-voltage-driven ciliary hydrogel microactuators

48. A foundation model for continuous glucose monitoring data

49. Coherent nonlinear X-ray four-photon interaction with core-shell electrons

50. Training large language models on narrow tasks can lead to broad misalignment

51. Direct observation of the Migdal effect induced by neutron bombardment

52. Exciplex-enabled high-efficiency, fully stretchable OLEDs

53. Microbiota-induced T cell plasticity enables immune-mediated tumour control

54. Dominant contribution of Asgard archaea to eukaryogenesis

55. Mosaic lateral heterostructures in two-dimensional perovskite

56. Retraction Note: Antibodies against endogenous retroviruses promote lung cancer immunotherapy

57. AI can turbocharge scientists’ careers — but limit their scope

58. What the future holds for AI – from the people shaping it

59. Cancer might evade immune defences by stealing mitochondria

60. Take Nature’s poll: do you have a side hustle alongside your PhD studies?

61. Beneath acid skies

62. Predicting the fate of tropical forests under intensifying heat

63. Three tips for scientific writing: a guide for graduate students

64. Six steps to protect researchers’ digital security

65. Daily briefing: Same-sex sex is a normal part of some primates’ lives

66. The infection enigma: why some people die from typically harmless germs

67. Do their ears hang low? The genetics of dogs’ adorable floppy ears

68. How to improve vaccine uptake: a huge study offers clues

69. Should the Loch Ness Monster have a scientific name?

70. The academic community failed Wikipedia for 25 years — now it might fail us

71. AI can spark creativity — if we ask it how, not what, to think

72. How did birds evolve? The answer is wilder than anyone thought

73. AlphaFold can help African researchers to do cutting-edge structural biology

74. AI writing tools could lead scholars from low-income countries to erase their own voices

75. Don’t assume that women’s low retraction rates reflect male ‘boldness’

76. No world-changing discoveries without biodiversity

77. Daily briefing: The neural circuit that can make it hard to start a difficult task

78. Same-sex sexual behaviour can help primates to survive — and reproduce

79. US scientists push back as Trump eyes Greenland

80. Developing super-tortillas to address malnutrition in Latin America

81. ‘We’re humans — brilliant and a mess’: Wikipedia founder Jimmy Wales on trust and optimism

82. Student mental health is in crisis — here’s how to help

83. AIs are biased toward some Indian castes — how can researchers fix this?

84. Daily briefing: Fusion reactor pushes plasma past crucial limit

85. Fresh starts: how to thrive when you leave academia

86. Ancient ‘snowball’ Earth had frigidly briny seas

87. NASA won’t bring Mars samples back to Earth: this is the science that will be lost

88. Can’t get motivated? This brain circuit might explain why — and it can be turned off

89. We need to talk about salaries in science

90. Getting to the (square) root of stock-market swings

91. ‘Coming out as a transgender scientist made me the best teacher I’ve ever been’

92. This shapeshifting polymer was inspired by octopus skin

93. To infinity and beyond Earth’s pale blue dot: Books in brief

94. Daily briefing: Octopus-inspired synthetic ‘skin’ changes appearance on demand

95. Chinese nuclear fusion reactor pushes plasma past crucial limit: what happens next

96. Disappearing ‘planet’ reveals a solar system’s turbulent times

97. Chatbots in therapy: do AI models really have ''trauma''?

98. Huge Chinese cell atlas reveals surprising immune variation among peoples

99. Putting immune cells into ‘night mode’ reduces heart-attack damage

100. Will mpox go global again? Research shows it''s evolving in curious ways

101. Author Correction: Structural insights into BCDX2 complex function in homologous recombination

102. Daily briefing: How 400-year-old sharks keep their vision sharp

103. Oldest known poison arrows show Stone Age humans’ technological talents

104. Octopus-inspired ‘synthetic skin’ changes colour and texture on demand

105. Blood protein thwarts deadly fungal disease

106. A way to identify the biological basis of gene–trait associations

107. Exotic quasiparticles glimpsed in graphene

108. Chronic pain could be eased by uncoupling the sensory and emotional experiences

109. How viral RNAs escape a host mechanism that controls translation

110. Of all the quarries: Casablanca fossils reveal African ancestors of Homo sapiens

111. Ultra-low-density exoplanets observed around a young star

112. The complex role of nutrients in cancer spread

113. Oral 4′-fluorouridine rescues nonhuman primates from advanced Lassa fever

114. Stress controls heterochromatin inheritance via histone H3 ubiquitylation

115. Evidence accumulation from experience and observation in the cingulate cortex

116. ipRGC properties prevent light from shifting the SCN clock during daytime

117. Small persistent humid forest clearings drive tropical forest biomass losses

118. Albumin orchestrates a natural host defence mechanism against mucormycosis

119. A mechanical ratchet drives unilateral cytokinesis

120. Distinct neuronal populations in the human brain combine content and context

121. Mimicking opioid analgesia in cortical pain circuits

122. An ancient DNA perspective on the Russian conquest of Yakutia

123. Intratumoural vaccination via checkpoint degradation-coupled antigen presentation

124. Mitochondrial transfer from glia to neurons protects against peripheral neuropathy

125. Soft photonic skins with dynamic texture and colour control

126. Aharonov–Bohm interference in even-denominator fractional quantum Hall states

127. Towards fibre-like loss for photonic integration from violet to near-infrared

128. Nutrient requirements of organ-specific metastasis in breast cancer

129. Neuro-epithelial circuits promote sensory convergence and intestinal immunity

130. Pulse heating and slip enhance charging of phase-change thermal batteries

131. Insights into DNA repeat expansions among 900,000 biobank participants

132. Genetic switch between unicellularity and multicellularity in marine yeasts

133. Early hominins from Morocco basal to the Homo sapiens lineage

134. Soft biodegradable implants for long-distance and wide-angle sensing

135. Bidirectional CRISPR screens decode a GLIS3-dependent fibrotic cell circuit

136. Prefrontal neural geometry of learned cues guides motivated behaviours

137. Climate change shifts the North Pacific storm track polewards

138. High-voltage anode-free sodium–sulfur batteries

139. An expanded registry of candidate cis-regulatory elements

140. Plastic landmark anchoring in zebrafish compass neurons

141. RNA-triggered Cas12a3 cleaves tRNA tails to execute bacterial immunity

142. Surface optimization governs the local design of physical networks

143. A young progenitor for the most common planetary systems in the Galaxy

144. A hidden diversity of ceratopsian dinosaurs in Late Cretaceous Europe

145. A framework for addressing racial and related inequities in conservation

146. A mysterious ancient fingerprint and a lemon-shaped planet — the stories you’ve missed

147. Systematic analyses of lipid mobilization by human lipid transfer proteins

148. Electrochemical defluorinative Matteson-type homologation

149. A troubleshooting guide to your flat-pack planet

150. Daily briefing: Animals without brains sleep too — hinting at why we sleep at all

151. ‘I rarely get outside’: scientists ditch fieldwork in the age of AI

152. Jellyfish sleep like humans — even though they don’t have brains

153. Artificial skin mimics the octopus’s art of disguise

154. Defossilize our chemical world

155. The poetic life and death of a glow-worm

156. Daily briefing: The human cells in our bodies that aren’t genetically ours

157. Why cancer can come back years later — and how to stop it

158. To improve resilience to climate change, track what endures

159. Retire ‘seminal’ from the scientific vocabulary

160. Help small-scale gold miners to transition away from mercury use

161. Rethink how we build AI to enable effective climate-change mitigation

162. Sunyaev–Zeldovich detection of hot intracluster gas at redshift 4.3

163. I see Mozambique’s baboons as windows into hominid evolution

164. Pandemic PhDs: graduates anxious, but optimistic, about the future

165. These women helped to shape quantum mechanics — it’s time to recognize them

166. Author Correction: Rewiring an olfactory circuit by altering cell-surface combinatorial code

167. Author Correction: Repulsions instruct synaptic partner matching in an olfactory circuit

168. Science in 2026: what to expect this year

169. Highly efficient LED device built by stacking layers of light-emitting perovskite

170. Sub-Saharan Africa has lost almost one-quarter of its pre-industrial biodiversity

171. How to reduce the environmental impact of wearable health-care devices

172. Economic inequality does not equate to poor well-being or mental health

173. Quantifying the global eco-footprint of wearable healthcare electronics

174. Random heteropolymers as enzyme mimics

175. A chiral fermionic valve driven by quantum geometry

176. Some of your cells are not genetically yours — what can they tell us about life and death?

177. Can boomerangs bounce?

178. Safe as houses

179. Put pressure on publishers to follow best practice — external regulation is the answer

180. Mummies give up their secrets — but not their mystery

181. Science in 2050: the future breakthroughs that will shape our world — and beyond

182. Audio long read: Will blockbuster obesity drugs revolutionize addiction treatment?

183. Probing pollutants: how I use penguin faeces to measure contaminants in Antarctica

184. Let 2026 be the year the world comes together for AI safety

185. Nine books to help shape your science career in 2026

186. Why academics should do more consulting — and how to make it work

187. The Nature Podcast highlights of 2025

188. Author Correction: Rolling back human pluripotent stem cells to an eight-cell embryo-like stage

189. Seeding opportunities for Black atmospheric scientists

190. Non-equilibrium snapshots of ligand efficacy at the μ-opioid receptor

191. NAC controls nascent chain fate through tunnel sensing and chaperone action

192. Daily briefing: Explore 2025 with Leif Penguinson

193. AI and quantum science take centre stage under Trump — but with little new proposed funding

194. ‘A serious problem’: peer reviews created using AI can avoid detection

195. Nature''s News & Views roundup of 2025

196. Oddly cool super-hot planet has an atmosphere it shouldn’t

197. Are we living in a parallel universe? The strange physics of Stranger Things

198. Author Correction: Cryo-EM structure of a natural RNA nanocage

199. Point of no returns: researchers are crossing a threshold in the fight for funding

200. Publisher Correction: Covalent targeted radioligands potentiate radionuclide therapy

201. US–Africa bilateral health deals won’t help against diseases that ignore borders

202. Dogma-defying signalling through G proteins could lead to better pain relief

203. Science in 2026: the events to watch for in the coming year

204. Hot spot: plants use infrared signals to say they’re ready to reproduce

205. Living water and whispering rocks: Books in brief

206. Trump team plans to break up ‘global mothership’ of climate science

207. Genes don’t explain what made humans different

208. How the Romans built their empire of concrete

209. Take the News & Views end-of-year quiz: vampire fungus, migratory moths and a 160-year-old mystery

210. Restoring youth to old immune cells: mRNA therapy turns back the clock.

211. Systematic maps reveal how human chromosomes are organized

212. A modular quantum processor made using phosphorus atoms in silicon

213. The Nature Podcast festive spectacular 2025

214. How common is Alzheimer’s? Blood-test study holds surprises

215. Mechanism for water formation on rocky exoplanets demonstrated in the lab

216. The hidden cost of video-call glitches

217. 3D nanolithography with metalens arrays and spatially adaptive illumination

218. Laser spectroscopy and CP-violation sensitivity of actinium monofluoride

219. Lesion-remote astrocytes govern microglia-mediated white matter repair

220. Spatiotemporal cellular map of the developing human reproductive tract

221. Human assembloids recapitulate periportal liver tissue in vitro

222. Titan’s strong tidal dissipation precludes a subsurface ocean

223. Prevalence of Alzheimer’s disease pathology in the community

224. Visualizing interaction-driven restructuring of quantum Hall edge states

225. The global hydrogen budget

226. An 11-qubit atom processor in silicon

227. Astrocyte CCN1 stabilizes neural circuits in the adult brain

228. Palaeometabolomes yield biological and ecological profiles at early human sites

229. An integrated view of the structure and function of the human 4D nucleome

230. Programmable 200 GOPS Hopfield-inspired photonic Ising machine

231. GTP release-selective agonists prolong opioid analgesic efficacy

232. Gene-specific selective sweeps are pervasive across human gut microbiomes

233. Transient hepatic reconstitution of trophic factors enhances aged immunity

234. Mazdutide versus placebo in Chinese adults with type 2 diabetes

235. Mazdutide versus dulaglutide in Chinese adults with type 2 diabetes

236. MIT fusion-lab head shot dead: a horror ''impossible to believe''

237. Immunological sin: how a person’s earliest flu infections dictate life-long immunity

238. Annual flu vaccines are far from ideal — this is why

239. A universal flu vaccine has proved challenging — could it finally be possible?

240. The quest to hatch a bird-flu vaccine

241. Could tracking animals’ health help to avert the next pandemic?

242. Flu’s link to cardiovascular disease shows why vaccination is essential

243. Virology’s most wanted: the influenza virus

244. Seven feel-good science stories to restore your faith in 2025

245. Beauty is in the eye of the beholder

246. Stopping the next flu pandemic

247. Is bird flu the next pandemic? The science so far

248. Author Correction: Neuroimmune cardiovascular interfaces control atherosclerosis

249. I’ve earned my PhD — what now?

250. Scientists skip key US meetings — and seize on smaller alternatives

251. Safety regulations for cloning and a compass that finds true north

252. How my institution strengthened research despite chronic underfunding

253. Science’s role in my Great British Sewing Bee success

254. AI is transforming the economy — understanding its impact requires both data and imagination

255. More than half of researchers now use AI for peer review — often against guidance

256. NSF softens grant-review rules to cope with backlog

257. Tracing pollution in the lives of Arctic seabirds

258. How fasting boosts breast cancer therapy

259. The best science images of 2025 — Nature’s picks

260. Giving a voice to animals: Laos’s national herpetologist on her day-to-day

261. Grant cuts, arrests, lay-offs: Trump made 2025 a tumultuous year for science

262. Despite all the negatives, 2025 showcased the power, resilience and universality of science

263. Author Correction: Unravelling cysteine-deficiency-associated rapid weight loss

264. Science sleuths raise concerns about scores of bioengineering papers

265. Revised estimates of CO2 sources and sinks improve global carbon accounting

266. China leads research in 90% of crucial technologies — a dramatic shift this century

267. Author Correction: Distinct fibroblast subsets drive inflammation and damage in arthritis

268. Author Correction: Cancer SLC43A2 alters T cell methionine metabolism and histone methylation

269. In praise of inefficiency, failure and friendship: ten galvanizing reads for this festive season

270. Giant 3D map shows almost every building in the world

271. Quantum computing ‘KPIs’ could distinguish true breakthroughs from spurious claims

272. Solar cells that combine multiple perovskite layers surpass 30% efficiency

273. The gift that shaped my career in science

274. Asteroids, antibiotics and ants: a year of remarkable science

275. Author Correction: Conservation and alteration of mammalian striatal interneurons

276. Australia’s world-first social media ban is a ‘natural experiment’ for scientists

277. This AI model ‘studied’ physics — and learnt to forecast extreme weather

278. Huge genetic study reveals hidden links between psychiatric conditions

279. Oldest known evidence of the controlled ignition of fire

280. Shared genetic risk in psychiatric disorders

281. The brain’s speech centre responds to universal and specific features of language

282. Genetically engineered mosquitoes block development of circulating malaria strains

283. Nuclear clocks could use electrical signals to keep time

284. A simple slipknot for precise force control

285. SOS: RNA-processing mechanism rescues genes from invasive DNA

286. A giant catalogue of microscopic species across Denmark

287. Gut micro-organisms associated with health, nutrition and dietary interventions

288. Mutations in mitochondrial ferredoxin FDX2 suppress frataxin deficiency

289. Causal modelling of gene effects from regulators to programs to traits

290. Agonists for cytosolic bacterial receptor ALPK1 induce antitumour immunity

291. Laser-based conversion electron Mössbauer spectroscopy of 229ThO2

292. Protected area management has significant spillover effects on vegetation

293. Somatic evolution following cancer treatment in normal tissue

294. Uncovering the role of LINE-1 in the evolution of lung adenocarcinoma

295. An RNA splicing system that excises DNA transposons from animal mRNAs

296. Mapping the genetic landscape across 14 psychiatric disorders

297. Neutrophils preserve energy storage in sympathetically activated adipocytes

298. A direct role for a mitochondrial targeting sequence in signalling stress

299. Hot droughts in the Amazon provide a window to a future hypertropical climate

300. Observation of deuteron and antideuteron formation from resonance-decay nucleons