The Nature Podcast highlights of 2025 (www.nature.com)
Author Correction: Rolling back human pluripotent stem cells to an eight-cell embryo-like stage (www.nature.com)
Seeding opportunities for Black atmospheric scientists (www.nature.com)
Non-equilibrium snapshots of ligand efficacy at the μ-opioid receptor (www.nature.com)
NAC controls nascent chain fate through tunnel sensing and chaperone action (www.nature.com)
Daily briefing: Explore 2025 with Leif Penguinson (www.nature.com)
AI and quantum science take centre stage under Trump — but with little new proposed funding (www.nature.com)
‘A serious problem’: peer reviews created using AI can avoid detection (www.nature.com)
Nature''s News & Views roundup of 2025 (www.nature.com)
Oddly cool super-hot planet has an atmosphere it shouldn’t (www.nature.com)
Are we living in a parallel universe? The strange physics of Stranger Things (www.nature.com)
Author Correction: Cryo-EM structure of a natural RNA nanocage (www.nature.com)
Point of no returns: researchers are crossing a threshold in the fight for funding (www.nature.com)
Publisher Correction: Covalent targeted radioligands potentiate radionuclide therapy (www.nature.com)
US–Africa bilateral health deals won’t help against diseases that ignore borders (www.nature.com)
Dogma-defying signalling through G proteins could lead to better pain relief (www.nature.com)
Science in 2026: the events to watch for in the coming year (www.nature.com)
Hot spot: plants use infrared signals to say they’re ready to reproduce (www.nature.com)
Living water and whispering rocks: Books in brief (www.nature.com)
Trump team plans to break up ‘global mothership’ of climate science (www.nature.com)
Genes don’t explain what made humans different (www.nature.com)
How the Romans built their empire of concrete (www.nature.com)
Take the News & Views end-of-year quiz: vampire fungus, migratory moths and a 160-year-old mystery (www.nature.com)
Restoring youth to old immune cells: mRNA therapy turns back the clock. (www.nature.com)
Systematic maps reveal how human chromosomes are organized (www.nature.com)
A modular quantum processor made using phosphorus atoms in silicon (www.nature.com)
The Nature Podcast festive spectacular 2025 (www.nature.com)
How common is Alzheimer’s? Blood-test study holds surprises (www.nature.com)
Mechanism for water formation on rocky exoplanets demonstrated in the lab (www.nature.com)
The hidden cost of video-call glitches (www.nature.com)
3D nanolithography with metalens arrays and spatially adaptive illumination (www.nature.com)
Laser spectroscopy and CP-violation sensitivity of actinium monofluoride (www.nature.com)
Lesion-remote astrocytes govern microglia-mediated white matter repair (www.nature.com)
Spatiotemporal cellular map of the developing human reproductive tract (www.nature.com)
Human assembloids recapitulate periportal liver tissue in vitro (www.nature.com)
Titan’s strong tidal dissipation precludes a subsurface ocean (www.nature.com)
Prevalence of Alzheimer’s disease pathology in the community (www.nature.com)
Visualizing interaction-driven restructuring of quantum Hall edge states (www.nature.com)
The global hydrogen budget (www.nature.com)
An 11-qubit atom processor in silicon (www.nature.com)
Astrocyte CCN1 stabilizes neural circuits in the adult brain (www.nature.com)
Palaeometabolomes yield biological and ecological profiles at early human sites (www.nature.com)
An integrated view of the structure and function of the human 4D nucleome (www.nature.com)
Programmable 200 GOPS Hopfield-inspired photonic Ising machine (www.nature.com)
GTP release-selective agonists prolong opioid analgesic efficacy (www.nature.com)
Gene-specific selective sweeps are pervasive across human gut microbiomes (www.nature.com)
Transient hepatic reconstitution of trophic factors enhances aged immunity (www.nature.com)
Mazdutide versus placebo in Chinese adults with type 2 diabetes (www.nature.com)
Mazdutide versus dulaglutide in Chinese adults with type 2 diabetes (www.nature.com)
MIT fusion-lab head shot dead: a horror ''impossible to believe'' (www.nature.com)
Immunological sin: how a person’s earliest flu infections dictate life-long immunity (www.nature.com)
Annual flu vaccines are far from ideal — this is why (www.nature.com)
A universal flu vaccine has proved challenging — could it finally be possible? (www.nature.com)
The quest to hatch a bird-flu vaccine (www.nature.com)
Could tracking animals’ health help to avert the next pandemic? (www.nature.com)
Flu’s link to cardiovascular disease shows why vaccination is essential (www.nature.com)
Virology’s most wanted: the influenza virus (www.nature.com)
Seven feel-good science stories to restore your faith in 2025 (www.nature.com)
Beauty is in the eye of the beholder (www.nature.com)
Stopping the next flu pandemic (www.nature.com)
Is bird flu the next pandemic? The science so far (www.nature.com)
Author Correction: Neuroimmune cardiovascular interfaces control atherosclerosis (www.nature.com)
I’ve earned my PhD — what now? (www.nature.com)
Scientists skip key US meetings — and seize on smaller alternatives (www.nature.com)
Safety regulations for cloning and a compass that finds true north (www.nature.com)
How my institution strengthened research despite chronic underfunding (www.nature.com)
Science’s role in my Great British Sewing Bee success (www.nature.com)
AI is transforming the economy — understanding its impact requires both data and imagination (www.nature.com)
More than half of researchers now use AI for peer review — often against guidance (www.nature.com)
NSF softens grant-review rules to cope with backlog (www.nature.com)
Tracing pollution in the lives of Arctic seabirds (www.nature.com)
How fasting boosts breast cancer therapy (www.nature.com)
The best science images of 2025 — Nature’s picks (www.nature.com)
Giving a voice to animals: Laos’s national herpetologist on her day-to-day (www.nature.com)
Grant cuts, arrests, lay-offs: Trump made 2025 a tumultuous year for science (www.nature.com)
Despite all the negatives, 2025 showcased the power, resilience and universality of science (www.nature.com)
Author Correction: Unravelling cysteine-deficiency-associated rapid weight loss (www.nature.com)
Science sleuths raise concerns about scores of bioengineering papers (www.nature.com)
Revised estimates of CO2 sources and sinks improve global carbon accounting (www.nature.com)
China leads research in 90% of crucial technologies — a dramatic shift this century (www.nature.com)
Author Correction: Distinct fibroblast subsets drive inflammation and damage in arthritis (www.nature.com)
Author Correction: Cancer SLC43A2 alters T cell methionine metabolism and histone methylation (www.nature.com)
In praise of inefficiency, failure and friendship: ten galvanizing reads for this festive season (www.nature.com)
Giant 3D map shows almost every building in the world (www.nature.com)
Quantum computing ‘KPIs’ could distinguish true breakthroughs from spurious claims (www.nature.com)
Solar cells that combine multiple perovskite layers surpass 30% efficiency (www.nature.com)
The gift that shaped my career in science (www.nature.com)
Asteroids, antibiotics and ants: a year of remarkable science (www.nature.com)
Author Correction: Conservation and alteration of mammalian striatal interneurons (www.nature.com)
Australia’s world-first social media ban is a ‘natural experiment’ for scientists (www.nature.com)
This AI model ‘studied’ physics — and learnt to forecast extreme weather (www.nature.com)
Huge genetic study reveals hidden links between psychiatric conditions (www.nature.com)
Oldest known evidence of the controlled ignition of fire (www.nature.com)
Shared genetic risk in psychiatric disorders (www.nature.com)
The brain’s speech centre responds to universal and specific features of language (www.nature.com)
Genetically engineered mosquitoes block development of circulating malaria strains (www.nature.com)
Nuclear clocks could use electrical signals to keep time (www.nature.com)
A simple slipknot for precise force control (www.nature.com)
SOS: RNA-processing mechanism rescues genes from invasive DNA (www.nature.com)
A giant catalogue of microscopic species across Denmark (www.nature.com)
Gut micro-organisms associated with health, nutrition and dietary interventions (www.nature.com)
Mutations in mitochondrial ferredoxin FDX2 suppress frataxin deficiency (www.nature.com)
Causal modelling of gene effects from regulators to programs to traits (www.nature.com)
Agonists for cytosolic bacterial receptor ALPK1 induce antitumour immunity (www.nature.com)
Laser-based conversion electron Mössbauer spectroscopy of 229ThO2 (www.nature.com)
Protected area management has significant spillover effects on vegetation (www.nature.com)
Somatic evolution following cancer treatment in normal tissue (www.nature.com)
Uncovering the role of LINE-1 in the evolution of lung adenocarcinoma (www.nature.com)
An RNA splicing system that excises DNA transposons from animal mRNAs (www.nature.com)
Mapping the genetic landscape across 14 psychiatric disorders (www.nature.com)
Neutrophils preserve energy storage in sympathetically activated adipocytes (www.nature.com)
A direct role for a mitochondrial targeting sequence in signalling stress (www.nature.com)
Hot droughts in the Amazon provide a window to a future hypertropical climate (www.nature.com)
Observation of deuteron and antideuteron formation from resonance-decay nucleons (www.nature.com)
Earliest evidence of making fire (www.nature.com)
Sterilization and contraception increase lifespan across vertebrates (www.nature.com)
Cross-regulation of [2Fe–2S] cluster synthesis by ferredoxin-2 and frataxin (www.nature.com)
Human gut M cells resemble dendritic cells and present gluten antigen (www.nature.com)
Erythropoietin receptor on cDC1s dictates immune tolerance (www.nature.com)
Gene-drive-capable mosquitoes suppress patient-derived malaria in Tanzania (www.nature.com)
Quantifying grain boundary deformation mechanisms in small-grained metals (www.nature.com)
The influence of short-lived halogens on atmospheric chemistry and climate (www.nature.com)
Fasting boosts breast cancer therapy efficacy via glucocorticoid activation (www.nature.com)
Neanderthals mastered fire — 400,000 years ago (www.nature.com)
Four young universities share their strategies for success (www.nature.com)
What would an AI university look like and how might it change education? (www.nature.com)
Will young universities set the pace in the age of AI? (www.nature.com)
Early detection could improve pancreatic cancer’s poor survival rates (www.nature.com)
Therapeutic vaccines can challenge pancreatic cancer before it takes hold (www.nature.com)
The pancreatic cancer models helping to drive innovation in the field (www.nature.com)
A breathalyser-style test for detecting pancreatic cancer (www.nature.com)
Six highlights from pancreatic cancer research (www.nature.com)
Pancreatic cancer is evasive. Is the nervous system the reason why? (www.nature.com)
Exposing a silent cancer (www.nature.com)
Glimmers of hope for a deadly disease (www.nature.com)
But only just (www.nature.com)
China is leading the world on AI governance: other countries must engage (www.nature.com)
Is your brain tired? Researchers are discovering the roots of mental fatigue (www.nature.com)
A poetic ode to eddies and an earwig’s brush with death (www.nature.com)
What will be the first AI-designed drug? These disease-fighting antibodies are top contenders (www.nature.com)
What we eat is making us obese and sick — but science shows solutions are within reach (www.nature.com)
Food will be more affordable — if we double funds for agriculture research now (www.nature.com)
Argentina must finish building the CART radio telescope (www.nature.com)
Drug woes won’t be tamed by US price regulations (www.nature.com)
Better models are needed to gauge the ecological impacts of reservoirs (www.nature.com)
Don’t overlook the value of co-supervision in PhD training (www.nature.com)
The first global pandemic treaty — and the woman who made it happen (www.nature.com)
This scientist found a new trick of the immune system by digging through cellular rubbish (www.nature.com)
This science sleuth revealed a retraction crisis at Indian universities (www.nature.com)
9,000 metres under the sea: this researcher found the deepest animal ecosystems on Earth (www.nature.com)
The visionary physicist who gave us a new way to view the cosmos (www.nature.com)
The Chinese finance whizz whose DeepSeek AI model stunned the world (www.nature.com)
The top US health director who stood up for science — and was fired (www.nature.com)
‘Giant step forward’ for Huntington’s — the scientist behind the first gene therapy (www.nature.com)
The baby whose life was saved by the first personalized CRISPR therapy (www.nature.com)
This scientist is breeding billions of mosquitoes to fight disease in Brazil (www.nature.com)
Nature’s 10: Ten people who shaped science in 2025 (www.nature.com)
Five years of COVID vaccines: how a breakthrough created a public-heath crisis (www.nature.com)
Home-field advantage: how local research leads to new discoveries (www.nature.com)
How to get science back into policymaking (www.nature.com)
Long-COVID research just got a big funding boost: will it find new treatments? (www.nature.com)
Five important financial moves for PhD students (www.nature.com)
Publisher Correction: CRISPR activation for SCN2A-related neurodevelopmental disorders (www.nature.com)
How the Royal Institution made science a seasonal spectacle (www.nature.com)
The Indian Ocean disaster is a climate tragedy — and needs more attention (www.nature.com)
AI is saving time and money in research — but at what cost? (www.nature.com)
These are a few of my favourite sounds: Books in brief (www.nature.com)
Fate of hepatitis B vaccine for US babies hangs in the balance (www.nature.com)
DeepSeek’s self-correcting AI model aces tough maths proofs (www.nature.com)
AI chatbots can persuade voters to change their minds (www.nature.com)
AI chatbots can sway voters with remarkable ease — is it time to worry? (www.nature.com)
China’s scientific clout is growing as US influence wanes: the data show how (www.nature.com)
Persuading voters using human–artificial intelligence dialogues (www.nature.com)
Aluminium is crucial to vaccines — and safe. Why are US advisers debating it? (www.nature.com)
Author Correction: Activity of caspase-8 determines plasticity between cell death pathways (www.nature.com)
Experimental vaccine prevents deadly allergic reactions in mice (www.nature.com)
Satellite swarms set to photobomb more than 95% of some telescopes’ images (www.nature.com)
Still no sign of hypothetical sterile-neutrino particle (www.nature.com)
Quarks in ‘exotic’ quartets prefer to stick together (www.nature.com)
Even in space, telescopes can’t escape photobombers (www.nature.com)
Order in which cancer-driving mutations occur affects the chance of tumour development (www.nature.com)
Primate embryo model leaps across developmental boundaries (www.nature.com)
A glasses-free 3D display uses AI to direct images straight to the viewer’s eyes (www.nature.com)
Decay of driver mutations shapes the landscape of intestinal transformation (www.nature.com)
Architecture of the neutrophil compartment (www.nature.com)
Homo sapiens-specific evolution unveiled by ancient southern African genomes (www.nature.com)
Viral RNA blocks circularization to evade host codon usage control (www.nature.com)
Search for light sterile neutrinos with two neutrino beams at MicroBooNE (www.nature.com)
Video-call glitches trigger uncanniness and harm consequential life outcomes (www.nature.com)
Built environment disparities are amplified during extreme weather recovery (www.nature.com)
Computational enzyme design by catalytic motif scaffolding (www.nature.com)
Satellite megaconstellations will threaten space-based astronomy (www.nature.com)
Determination of the spin and parity of all-charm tetraquarks (www.nature.com)
The Microflora Danica atlas of Danish environmental microbiomes (www.nature.com)
TSC tunes progenitor balance and upper-layer neuron generation in neocortex (www.nature.com)
Dated gene duplications elucidate the evolutionary assembly of eukaryotes (www.nature.com)
Modelling late gastrulation in stem cell-derived monkey embryo models (www.nature.com)
Whole-genome landscapes of 1,364 breast cancers (www.nature.com)
Sterile-neutrino search based on 259 days of KATRIN data (www.nature.com)
A place-based assessment of biodiversity intactness in sub-Saharan Africa (www.nature.com)
Computational design of metallohydrolases (www.nature.com)
Photobombing satellites could ruin the night sky for space telescopes (www.nature.com)
Building mentally healthy cities with neuroscience (www.nature.com)
How cities can keep their cool (www.nature.com)
Cities aren’t built for women — it’s time to change that (www.nature.com)
Wooden skyscrapers point the way to more sustainable cities (www.nature.com)
Geothermal networks let cities warm and cool as one (www.nature.com)
Cities are embracing nature for flood defence (www.nature.com)
Data drive city transportation forwards (www.nature.com)
Darleane C. Hoffman obituary: chemist who expanded the periodic table (www.nature.com)
Growing cities face mounting challenges (www.nature.com)
A bothy among the stars (www.nature.com)
Author Correction: Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis (www.nature.com)
China accounts for more than half of leading output in the applied sciences (www.nature.com)
‘Anyone hired a student before?’ How a group of novice lab leaders are supporting each other (www.nature.com)
Author Correction: Seismic detection of a 600-km solid inner core in Mars (www.nature.com)
AI reviewers are here — we are not ready (www.nature.com)
Retraction Note: The economic commitment of climate change (www.nature.com)
The ‘silent’ brain cells that shape our behaviour, memory and health (www.nature.com)
This is the world’s largest spider web — November’s best science images (www.nature.com)
Practical alternative to explosive reaction will improve lab safety (www.nature.com)
Bulk superconductivity up to 96 K in pressurized nickelate single crystals (www.nature.com)
Don’t downplay problems of bullying and harassment in academia (www.nature.com)
Towns lag behind the switch to standard time (www.nature.com)
Author Correction: The first-principles phase diagram of monolayer nanoconfined water (www.nature.com)
Great science happens in great teams — research assessments must try to capture that (www.nature.com)
‘Fire amoeba’ survives in hotter conditions than any other complex cell (www.nature.com)
Author Correction: Video‐rate tunable colour electronic paper with human resolution (www.nature.com)
Why universities need to radically rethink exams in the age of AI (www.nature.com)
Alternatives to animal research are not inherently more ethical (www.nature.com)
Drinking water is at risk during warfare — better protections are needed (www.nature.com)
Ease the EU postdoc job market with better routes to innovation (www.nature.com)
Memes reveal threats to graduate-student mental health (www.nature.com)
Will blockbuster obesity drugs revolutionize addiction treatment? (www.nature.com)
Antibodies and T cells join forces for sustained HIV remission (www.nature.com)
Correlates of HIV-1 control after combination immunotherapy (www.nature.com)
Sustained HIV-1 remission after heterozygous CCR5Δ32 stem cell transplantation (www.nature.com)
CD8 T cell stemness precedes post-intervention control of HIV viremia (www.nature.com)
Climbing through the silver mine: my work as a geologist (www.nature.com)
Spineless creatures, possibly the world’s oldest beer receipt and more: 2025’s best Books in brief (www.nature.com)
Nature at its weirdest: what metamorphosis reveals about science and ourselves (www.nature.com)
David Baltimore obituary: virologist whose enzyme discovery transformed understanding of cancer and HIV/AIDS (www.nature.com)
China wants to lead the world on AI regulation — will the plan work? (www.nature.com)
Cooking up a storm of air pollution (www.nature.com)
The mystery of emerald green — cracked (www.nature.com)
AI finds signs of life in ancient rocks (www.nature.com)
Editorial Expression of Concern: Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells (www.nature.com)
Audio long read: Faulty mitochondria cause deadly diseases — fixing them is about to get a lot easier (www.nature.com)
Author Correction: Diversity-oriented synthesis yields novel multistage antimalarial inhibitors (www.nature.com)
Author Correction: Evidence for improved DNA repair in the long-lived bowhead whale (www.nature.com)
Laser cooling traps more antimatter atoms than ever before (www.nature.com)
A structured system: the secrets of Germany’s scientific reputation (www.nature.com)
Large language models are biased — local initiatives are fighting for change (www.nature.com)
Author Correction: Nasal delivery of an IgM offers broad protection from SARS-CoV-2 variants (www.nature.com)
Major AI conference flooded with peer-reviews written fully by AI (www.nature.com)
Author Correction: Inhibiting membrane rupture with NINJ1 antibodies limits tissue injury (www.nature.com)
Author Correction: Matrix viscoelasticity promotes liver cancer progression in the pre-cirrhotic liver (www.nature.com)
AlphaFold is five years old — these charts show how it revolutionized science (www.nature.com)
Land-use changes threaten the safety net for birds (www.nature.com)
Shape-shifting electrodes tune optical-frequency converter (www.nature.com)
Ancient DNA offers clues about mysterious prehistoric settlement in China (www.nature.com)
Weighing up the wild-meat harvest in Amazonia (www.nature.com)
Is there lightning on Mars? (www.nature.com)
Mystery owner of African hominin foot identified (www.nature.com)
Double whammy: drugs that inhibit kinase enzymes also speed up their disposal (www.nature.com)
A distinctive human genetic lineage persisted in central Argentina for 8,500 years (www.nature.com)
Yarns and fabrics that bend or stiffen under magnetic fields (www.nature.com)
Digging into the mechanisms that underlie soil production (www.nature.com)
Long-read metagenomics reveals phage dynamics in the human gut microbiome (www.nature.com)
Operating two exchange-only qubits in parallel (www.nature.com)
Healthy forests safeguard traditional wild meat food systems in Amazonia (www.nature.com)
Entanglement-enhanced nanoscale single-spin sensing (www.nature.com)
Progressive coevolution of the yeast centromere and kinetochore (www.nature.com)
Detection of triboelectric discharges during dust events on Mars (www.nature.com)
Glasses-free 3D display with ultrawide viewing range using deep learning (www.nature.com)
Land-use change undermines the stability of avian functional diversity (www.nature.com)
No meta-analytical effect of economic inequality on well-being or mental health (www.nature.com)
Evolution of taste processing shifts dietary preference (www.nature.com)
New finds shed light on diet and locomotion in Australopithecus deyiremeda (www.nature.com)
Ancient DNA from Shimao city records kinship practices in Neolithic China (www.nature.com)
Inhibitors supercharge kinase turnover through native proteolytic circuits (www.nature.com)
Inhibitory PD-1 axis maintains high-avidity stem-like CD8 T cells (www.nature.com)
iHALT unlocks liver functionality as a surrogate secondary lymphoid organ (www.nature.com)
Ethylene modulates cell wall mechanics for root responses to compaction (www.nature.com)
Multi-qubit nanoscale sensing with entanglement as a resource (www.nature.com)
Vicarious body maps bridge vision and touch in the human brain (www.nature.com)
Slipknot-gauged mechanical transmission and robotic operation (www.nature.com)
Building compositional tasks with shared neural subspaces (www.nature.com)
Ferroelectric transistors for low-power NAND flash memory (www.nature.com)
NSD2 targeting reverses plasticity and drug resistance in prostate cancer (www.nature.com)
Thalamocortical transcriptional gates coordinate memory stabilization (www.nature.com)
These ‘programmable’ knots harness physics to make surgical stitches safer (www.nature.com)
This is what lightning on Mars sounds like (www.nature.com)
Trump''s AI ‘Genesis Mission'': what are the risks and opportunities? (www.nature.com)
Author Correction: Photocatalytic low-temperature defluorination of PFASs (www.nature.com)
How to stop the revolving door of German academia (www.nature.com)
The Venus project (www.nature.com)
Why the world must wake up to China’s science leadership (www.nature.com)
‘They don’t have symptoms’: CAR-T therapies send autoimmune diseases into remission (www.nature.com)
ADHD diagnoses are growing. What’s going on? (www.nature.com)